重度子痫前期患者血流动力学和胎盘病理变化对妊娠结局的影响  

Severe hemodynamics of Preeclampsia and Placental Pathological changes and Pregnancy outcome

作　　者：周秀兰[1] 

机构地区：[1]广东省深圳市龙岗区妇幼保健院产科,广东深圳518072

出　　处：《中国临床医生杂志》2014年第3期30-32,共3页Chinese Journal For Clinicians

摘　　要：目的研究重度子痫前期患者血流动力学和胎盘病理改变对妊娠结局的影响。方法重度子痫前期患者70例为观察组,同期正常妊娠妇女80例为对照组,分析两组子宫、脐动脉血流动力学和胎盘病理变化及妊娠结局。结果对照组脐动脉S/D、PI和RI值均低于观察组,差异有显著性(P<0.05);对照组Survivin表达低于观察组,CasPase-3表达高于观察组,差异有显著性(P<0.05);对照组FGR、胎儿窘迫、低出生体重、新生儿窒息和围产儿死亡率均明显低于观察组,差异有显著性(P<0.05)。结论临床中需要严密监测子痫前期妇女子宫动脉和脐动脉S/D、RI、PI值,结合胎儿心电监护和胎儿生物功能评分,适时终止妊娠,改善围产儿预后。Objective To study the effects of severe Preeclampsia hemodynamics and Placental Pathological changes on Pregnancy outcome patients with severe Preeclampsia. Method 70 Patients with severe Preeclampsia in our hos-pital as observation group,80 cases of the expectant normal Pregnant women as control group,uterine and umbilical arterial blood changes in hemodynamics and Placental Pathology and Pregnancy outcome in the two groups were ana-lyzed. Result Umbilical artery S/D,PI and RI values in the control group were lower than the those in the observa-tion group,there was statistically significant （P〈0. 05）. The expression of Survivin was less the control group than that in the observation group,the expression of Caspase-3 was higher than that in the observation group,there were statistically significant （P〈0. 05）;FGR,fetal distress,low birth weight,neonatal asPhyxia and Perinatal mortality in the control group were significantly lower than those in the observation group,there were statistically significant（ P〈0. 05）. Discussion We need close monitoring of S/D、 RI、PI values for uterine artery and umbilical artery, com-bined with fetal ECG and fetal biological function scores, to timely terminate Pregnancy, improve Perinatal out-comes.

关 键 词：重度子痫前期 子宫动脉 脐动脉 妊娠结局 

分 类 号：R714.24[医药卫生—妇产科学]