猪瘟疫苗田间免疫效果监测  

A Monitoring of the Field Immunity Efficacy of Classical Swine Fever Vaccine

作　　者：何长生[1] 朱良强[1] 占松鹤[1] 王军[1] 沈艳[1] 刘华[1] 周迎春[1] 陈静[1] 

机构地区：[1]安徽省动物疫病预防与控制中心,合肥230091

出　　处：《中国兽药杂志》2014年第3期15-18,共4页Chinese Journal of Veterinary Drug

摘　　要：为准确掌握猪瘟疫苗免疫效果,2010-2012年对投放安徽省的猪瘟疫苗免疫效果进行了监测。采用抗体阻断ELISA方法,检测了454个猪场7439份免疫猪瘟弱毒活疫苗1个月左右的血清中猪瘟免疫抗体水平。结果显示,安徽省猪瘟疫苗免疫效果总体良好,免疫抗体合格率超过了70%;脾淋组织苗和细胞苗免疫效果相当,但脾淋组织苗免疫效果稳定,细胞苗免疫效果稳定性较差;不同厂家疫苗免疫效果参差不齐。In order to know well the immunity efficacy of classical swine fever（CSF） vaccine, from 2010 to 2012, we had monitored the immunity efficacy of classical swine fever vaccine which was used in Anhui province. 7439 swineserums collected from 454 swine farms that had been immunized with CSF vaccine for one month or so had been detected for the antibody titer of CSFV by antibody blocking ELISA. The results indicated that the immunity efficacy of CSF vaccine was good, and the positive rate of immune antibody exceeded 70% which was demanded by MOA of China. The immunity efficacy of CSF vaccine of both spleen and lymph tissue origin and tissue culture origin was not much different, but the immunity efficacy of spleen and lymph tissue origin was steady, and the tissue culture origin was unsteady. Furthermore, the immunity efficacy of CSF vaccine from different manufactures was different.

关 键 词：猪瘟疫苗 免疫效果 监测 抗体阻断ELISA 

分 类 号：S858.28[农业科学—临床兽医学]