藏猪低氧适应的血液生理指标研究  

Study on Blood Physiological Indicators of Adaptation to Hypoxia in Tibet Pig

作　　者：孔小艳[1] 苟潇[1] 马腾[1] 冷静[1] 毛华明[1] 杨舒黎[1] 

机构地区：[1]云南农业大学、云南省动物营养与饲料科学重点实验室,云南昆明650201

出　　处：《云南农业大学学报（自然科学版）》2014年第2期297-300,共4页Journal of Yunnan Agricultural University:Natural Science

基　　金：国家高技术研究发展计划(“863”计划)(2013AA102503);国家自然基金项目(31060301);NSFC-云南联合基金(U1036604)

摘　　要：藏猪作为青藏高原土著品种是很好的低氧适应研究模式动物。本研究选择藏猪(海拔3 700 m左右)、大河猪(海拔2 300 m左右)、明光小耳猪(海拔1 900 m左右)和滇南小耳猪(海拔550 m左右)等4个连续海拔分布猪种进行血液生理比较,共完成7项与氧气运输相关的血液生理指标检测。结果显示,藏猪红细胞数[RBC,(8.61±0.89)×1012/L]、血红蛋白浓度[HGB,(172.51±21.39)g/L]和红细胞压积[HCT,(53.02±6.39)%]3个指标远高于明光小耳猪(8.61±0.89,109.63±11.18,39.24±3.89)和滇南小耳猪(6.72±0.81,104.83±9.4,35.22±3.2)(P<0.01),平均红细胞体积[MCV,(61.65±3.52)fL]、平均红细胞血红蛋白含量[MCH,(19.99±1.24)Pg]和平均红细胞血红蛋白浓度[MCHC,(324.8±8.52)g/L]与后两者差异极显著(P<0.01),而2 300 m海拔大河猪各项指标均处于中间。结果表明,与氧气运输相关血液生理指标依海拔升高而升高;高的血红蛋白浓度是藏猪低氧适应的生理表征;而高的血红蛋白浓度主要来源于红细胞数增加。Tibet pig as the qinghai-tibet plateau indigenous breed,was very good model animal for low oxygen adaptation.Four breeds were chosen and measured 7 indicators that is related with the oxygen transport,as Tibet pig （about altitude of 3700 meters）,Dahe pig （about altitude of 2300 meters）,Mingguanxiaoer pig （about altitude of 1900 meters） and Diannanxiaoer pig （about altitude of 550 meters）.The results showed that Tibet pig had far higher RBC [（8.61-±0.89） × 1012/L],HGB [（172.51 ± 21.39） g/L] and HCT [（53.02 ± 6.39）%] compared with Mingguanxiaoer pig （8.61 ±-0.89,109.63 ±-11.18,39.24 ± 3.89） and Diannanxiaoer pig （6.72 ± 0.81,104.83 ±9.4,35.22±3.2） （P〈0.01）.In MCV [（61.65±3.52） fL],MCH [（19.99±1.24） Pg] and MCHC [（324.8-±8.52） g/L],Tibet pig was significantly higher than both of them,and the indexes of 2300m altitude Dahe pig in the middle.It indicated that blood physiological indicators of oxygen transport rises with the altitude rises of inhabitation.High RBC,contributing to increasing number of red blood cells,was physiological characterization of Tibet pig in hypoxia adapting.

关 键 词：藏猪 血液生理 海拔梯度 低氧适应 

分 类 号：S828.1[农业科学—畜牧学]