江苏省性病监测点治疗淋病使用抗生素情况调查  

Clinical antibiotic-use survey for gonorrhea treatment in Jiangsu province

作　　者：丁建平[1] 刘晓燕[1] 胡海洋[1] 陈国红[1] 邱涛[1] 徐金水[1] 傅更锋[1] 还锡萍[1] 羊海涛[1] 王小亮[1] 

机构地区：[1]江苏省疾病预防控制中心性病艾滋病防制所,江苏南京210009

出　　处：《南京医科大学学报（自然科学版）》2014年第1期90-93,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏预防医学项目(Y201029)

摘　　要：目的:分析江苏省临床医生治疗淋病使用抗生素的情况,为制订淋病的防治策略提供科学依据。方法:采用整群抽样、面对面访问的方法,对全省13个性病监测点的195名临床医生临床治疗淋病使用抗生素情况进行了调查,使用Logistic回归模型进行多因素分析。结果:在调查的195名临床医生中,联合用药的占56.41%,联合用药中以国家指南作为依据的为88名,占到80%,合并其他感染和个人经验和习惯的分别占了18.19%和1.82%;以头孢作为首选药治疗的占87.69%;医生所在医院类别和所在科室类别对淋病治疗用药的影响较大(P<0.05);在多因素分析中,皮肤病医院多倾向于联合用药(P<0.001),并倾向于使用除头孢曲松钠以外的其他头孢类抗生素治疗淋病(P<0.001),皮肤科医生在联合用药时更喜欢按照个人习惯和经验而不是按照国家指南来治疗淋病(P<0.05)。结论:临床医生对淋病治疗标准的掌握还有欠缺,尤其是应加强皮肤病性病医院和医生治疗淋病临床用药的培训,不断提高淋病的诊疗水平,更好地控制性病艾滋病在我省的传播。Objective：To analyze clinical data of gonorrhea treatment with antibiotics in Jiangsu province and provide scientific basis for gonorrhea control strategy. Methods：With cluster sampling and face-to-face interview,195 clinical doctors in 13 STD monitoring spots in Jiangsu were investigated with clinical use of antibiotics for gonorrhea treatment. Logistic multifactor regression model was used for multifactor analysis. Results：Among 195 clinical doctors investigated,56.41% of them applied the combination drug therapy;88 doctors were in accordance with National Guidelines during the therapy,accounting for 80%. The combination of other infections and personal experiences and habits accounted for 18.19% and 1.82%,respectively. Those who take cephalosporins as the first choice accounted for 87.69%. The variantion of hospitals and departments had a big influence on the treatment strategy for gonorrhea（P 〈 0.05）. With multifactor analysis,dermatosis specialized hospitals were likely to use combination drug therapy（P 〈 0.001）,and preferred other cephalosporins antibiotics rather than ceftriaxone sodium for gonorrhea treatment（P 〈 0.001）. Instead of the National Guidelines,dermatologists mostly relied on personal habits and experiences to treat gonorrhea（P 〈 0.05）. Conclusion：It is necessary to strengthen the awareness of gonorrhea treatment standards for clinical doctors,especially for the doctors in dermatosis specialized hospitals. Clinical drug application training should be enhanced to improve the level of diagnosis and treatment of gonorrhea,and to better control the STD/AIDS transmission in Jiangsu province.

关 键 词：淋病 抗生素 头孢类抗生素 治疗 性病 

分 类 号：R759.2[医药卫生—皮肤病学与性病学]