女性泌尿生殖道支原体感染分布情况及耐药分析  

Female urogenital mycoplasma infection and drug resistance analysis

作　　者：孟宪芹[1] 

机构地区：[1]北京市大兴区妇幼保健院,北京102600

出　　处：《西北药学杂志》2014年第2期191-192,共2页Northwest Pharmaceutical Journal

摘　　要：目的对女性泌尿生殖道支原体感染分布情况及药物敏感进行分析。方法选择2011年1月至2013年5月门诊2 218例女性疑似泌尿生殖道感染患者,采用液体培养法检测,研究支原体分布情况及耐药性。结果 2 218例宫颈分泌物标本中支原体呈阳性1 266例,检出率为57.08%,1 266例支原体感染者液体培养法结果显示,解脲支原体感染率为72.51%,Mh感染率为4.58%,解脲支原体和人型支原体混合感染率为22.91%。敏感性较高的抗菌药物:解脲支原体感染为红霉素、阿奇霉素、克拉霉素、强力霉素;人型支原体感染为克林霉素、强力霉素;解脲支原体与人型支原体混合感染为强力霉素。结论疑似泌尿生殖道感染女性患者进行支原体检测及药物敏感试验,对临床治疗有重要指导意义,可提高泌尿生殖道支原体感染治疗水平。Objective To analyze the female urogenital tract mycoplasma infection and drug resistance .Methods From January 2011 to May 2013 in our hospital 2 218 outpatient cases of suspected female urogenital tract infection patients were studied by using the liquid culture method .Results In 2 218 cases ,1 266 cases were positive for mycoplasma ,the positive detection rate（1 266/2 218） 57 .08% .Among them 1 166 cases were Urea plasma urealyticum（Uu） ,infection rate（918/1 266）72 .51% ;Mycoplasmahominis （Mh） infection rate was （58/1 266） 4 .58% ,Uu and Mh mixed infection rate（290/1 266） was 22 .91% .Uu infection showed a higher sensitivity to antibiotics erythromycin ,azithromycin ,clarithromycin ,and doxycycline ;Mh-infection showed relatively high sensitivity to antimicrobial drugs ,clindamycin ,doxycycline;Uu＋ Mh mixed infection showed higher sensitivity to doxycycline . Conclusion The drug sensitivity test is important in clinical treatment of suspected female genitourinary tract infections .

关 键 词：支原体感染 解脲支原体 人型支原体 抗菌药物敏感试验 

分 类 号：R984[医药卫生—药品]