颈动脉内膜中层厚度与脑卒中的关系及中药干预进展  

Relationship of stroke and carotid intima-media thickness and traditional Chinese medicine intervention progress: a review

作　　者：陈亚[1] 李亚娟[1] 卞卡[1,2] 

机构地区：[1]上海中医药大学穆拉德中药现代化研究中心,上海201203 [2]美国乔治华盛顿大学生物化学与分子生物学系,华盛顿dc20052

出　　处：《中国中药杂志》2014年第5期759-764,共6页China Journal of Chinese Materia Medica

基　　金：国家"重大新药创制"科技重大专项(2009ZX09311-003)

摘　　要：脑卒中是威胁人类健康的重大疾病之一,及时的早期治疗对脑卒中的防治十分重要。颈动脉内膜中层厚度(carotid intima-media thickness,CIMT)是诊断脑卒中的一个非倾入性指标,且是一个独立的预测因子,其增厚程度可以及时反映出脑卒中的进展情况,为脑卒中早期治疗提供诊断依据。该研究通过对CIMT与脑卒中及其危险因素的关系的阐述,突出强调了CIMT在预测脑卒中方面的重要作用;通过对CIMT可能的增厚机制的概述,为CIMT的治疗提供切入点,以期对CIMT的中药治疗起到指导作用。Stroke is one of the major diseases that threaten human health, early diagnosis and treatment are very important for stroke. Carotid intima-media thickness （CIMT） is measured noninvasively to diagnosis stroke, and it is a independent predictor for stroke because its thickening can timely predict the incidence and development of stroke. As an important predictor of cardiovascular disease, more and more attention is played on CIMT. In this review, we will make a summary on the important role of CIMT in stroke and the mechanisms of carotid intima-media thickening in stroke as well as the potential use of traditional Chinese medicine in treating carotid intima-media thickening.

关 键 词：颈动脉内膜中层厚度 脑卒中 颈动脉内膜中层增厚机制 中药干预 综述 

分 类 号：R277.7[医药卫生—中医学]