樟科药用植物山鸡椒的化学成分和药理活性研究进展  

A phytochemical and pharmacological advance on medicinal plant Litsea cubeba( Lauraceae)

作　　者：张水英[1,2] 郭强[1,2] 高小力[1] 郭志琴[1,2] 赵云芳[1] 柴兴云[1] 屠鹏飞[1] 

机构地区：[1]北京中医药大学中药现代研究中心,北京100029 [2]北京中医药大学中药学院,北京100102

出　　处：《中国中药杂志》2014年第5期769-776,共8页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81303309);教育部留学回国人员科研启动基金项目(2013-07)

摘　　要：山鸡椒是樟科木姜子属植物,其根、茎和果实均可入药,具有祛风散寒、理气止痛等功效,在民间应用广泛。该植物主要含有生物碱类,特别是阿朴啡生物碱,也含有少量的黄酮、木脂素及其他类成分。相关药理研究显示,山鸡椒在治疗心血管疾病、抗肿瘤、抗炎、提高免疫力、平喘抗过敏、抗氧化、抗菌、杀虫等多方面都有较好的效果。该文对山鸡椒的化学成分及药理活性进行了全面的归纳,以期对本种药用植物的综合研究和应用提供参考。Litsea cubeba is one of aromatic medicinal plant belonging to family Lauraceae. The roots, stems and fruits of L. cubeba have been widely applied as folk medicines in some districts in China for relieving rheumatism and cold, regulating Qi （ me- ridian） to alleviate pain. Previous studies revealed that this species contains major alkaloids, in specific aporphines, and minor fla- vonoids, lignans as well. Related pharmacological investigations demonstrated its activities and clinical applications on cardiovascular diseases, anti-cancer, against rheumatoid arthritis, relieving asthma and anti-allergic effects, as anti-oxidants, and so on. As an effort for further exploration of this bioactive ingredients and potential drug development, this paper summarizes most phytochemical and phar- macological results. Further, future prospects are also included.

关 键 词：樟科 山鸡椒 化学成分 药理活性 综述 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]