从中药注射剂质量标准分析其不良反应成因  

Analyze causes of adverse reactions induced by traditional Chinese medicine injections from its quality standards

作　　者：崔宏玉 梁爱华[2,1] 

机构地区：[1]首都医科大学中医药学院,北京100069 [2]中国中医科学院中药研究所,北京100700

出　　处：《中国中药杂志》2014年第5期934-940,共7页China Journal of Chinese Materia Medica

基　　金：国家科技支撑计划项目(2006BAI14B05);国家“重大新药创制”科技重大专项(2009ZX09301-005)

摘　　要：通过检索中国知网(CNKI)1983—2013年128种中药注射剂不良反应文献报道,从中药注射剂质量标准分析由中药注射剂导致的不良反应的成因,为提高中药注射剂的安全性并完善其质量标准提供思路。该综述提示中药注射剂不良反应的发生与中药组成味数关系不大,但与药物本身、辅料、溶媒的选择关系紧密,而由这些方面引起的不良反应大多数都可通过完善中药注射剂质量标准得到有效控制。Reviewing the literatures about adverse reactions induced by traditional Chinese medicine injections （TCMI） reported on CNKI from 1983 to 2013. Analyzing the causes of adverse reactions induced by TCMI from its quality standards. Provide ideas for improving security of TCMI and completing its quality standards. This review indicates that TCMI-indnced adverse reactions have little relationship with the number of compositions, but have tight connection with chemical ingredients and solvents. Adverse reactions can be decreased by perfecting the quality standards of TCMI.

关 键 词：中药注射剂质量标准 中药注射剂 不良反应 

分 类 号：R286[医药卫生—中药学]