布鲁氏菌疫苗的研究现状  

Current Research Status of Brucella Vaccine

作　　者：付莹莹[1,2] 秦贵信[1] 钱军[2,3] 赵思言[2,3] 郑关雨[1,2] 孙玉成[2,3] 万家余[2,3] 刘文森[2,3] 刘林娜[2,3] 

机构地区：[1]吉林农业大学动物科学技术学院,吉林长春130118 [2]军事医学科学院军事兽医研究所,吉林长春130122 [3]吉林省人兽共患病预防与控制重点实验室,吉林长春130122

出　　处：《中国畜牧兽医》2014年第3期258-261,共4页China Animal Husbandry & Veterinary Medicine

基　　金：国家863课题(2012AA022006);后勤科研重大项目(AWS12J005)

摘　　要：布鲁氏菌病是由布鲁氏菌引起的一种人畜共患传染病,该病不仅严重影响畜牧业的健康发展,对人类健康和社会公共卫生安全也存在着很大的威胁。现阶段对动物的主要防制措施为接种疫苗,国内外现已存在多个弱毒活疫苗,每种疫苗均各有利弊,目前尚无适合人类使用的疫苗,各个实验室也通过基因工程等技术手段来积极研制重组弱毒疫苗、分子标记疫苗、DNA疫苗等新型疫苗,作者现就新型疫苗的研究现状作一综述。Brucellosis caused by Brucella is a zoonotic infectious disease, and not only the serious influence to the healthy development of animal husbandry, but also to human health and public health security that exist a lot of threats. To the current prevention and control measures for animal vaccination, domestic and foreign existing multiple weak vaccines, each vaccine has its advantages and disadvantages, there is no vaccine for human currently, the laboratorys have used genetic engineering and other technical means to actively develop new vaccines, such as recombinant attenuated vaccines and marker vaccines, DNA vaccines and so on, this paper introduces the research status of new vaccines.

关 键 词：布鲁氏菌病 布鲁氏菌 新型疫苗 

分 类 号：S852.61[农业科学—基础兽医学]