镇肝熄风汤治疗高血压随机平行对照研究  

Zhenganxifeng Decoction in the Treatment of Hypertension, Randomized Parallel Controlled Study

作　　者：张理[1] 

机构地区：[1]厦门大学附属中山医院中医科,厦门361000

出　　处：《实用中医内科杂志》2013年第8期15-17,共3页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[目的]观察镇肝熄风汤治疗高血压疗效。[方法]使用随机平行对照方法,将68例门诊患者按就诊时间分为两组。对照组34例苯磺酸氨氯地平片,5mg/次,1次/d,口服。治疗组34例镇肝熄风汤(怀牛膝30g,生赭石、生牡蛎各25g,生龙骨20g,生麦芽、茵陈各15g,生龟甲、生白芍、川楝子、天冬、玄参各10g,甘草5g),1剂/d,水煎200mL,早晚口服;耳鸣加蝉蜕15g;恶心、呕吐加半夏10g;心烦燥热加茯神、山栀子、黄芩各10g;头晕、头痛加珍珠母30g,石决明20g,夏枯草10g。连续治疗30d为1疗程。观测临床症状、血压、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效21例,有效10例,无效3例,总有效率91.18%。对照组显效17例,有效13例,无效4例,总有效率88.24%。治疗组疗效优于对照组(P<0.05)。血压两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]镇肝熄风汤治疗高血压效果显著,值得推广。[ Objective ] To observe the curative effect of tranquilizing liver wind Decoction in the treatment of hypertension. [ Methods ] Using randomized controlled methods, 68 patients were divided into two groups. A control group of 34 cases Amlodipine Besylate Tablets, 5mg/, 1 /d, oral. The treatment group of 34 cases of Zhenganxifeng Decoction （ Huainiuxi 30g, Shengzhushi, Shengmuli each 25g, Shenglonggu 20g, Shengmaiya, Yinchen each 15g, Shengguijia, Shengbaishao, Chuanlianzi, Tiandong, Xuanshen each 10g, Gancao 5g ）, 1 doses of/d, water simmer in water 200mL, sooner or later, tinnitus add Chantui 15g; nausea, vomiting add Banxia 10g; upset hot plus Fushen, Shanzhizi, Huangqin each 10g; dizziness, headache add Zhenzhumu 30g, Shijueming 20g, Xiakucao 10g. Continuous treatment with 30d for 1 courses. Observation of clinical symptoms, blood pressure, adverse reaction. 1 courses of treatment, the curative effect. 21 cases of group therapy. [ Results ] 10 cases were effective, 3 cases ineffective, the total efficiency of 91.18%. The control group was 17 cases, effective 13 cases, invalid 4 cases, the total efficiency of 88.24%. The treatment group was better than control group （ P〈 0.05 ） . The blood pressure of two groups were improved （ P〈 0.05 ）, the treatment group was better than the control group （ P〈 0.05 ） . [ Conclusion ] Zhenganxifeng Decoction in the treatment of hypertensive effect is significant, worthy of promotion.

关 键 词：高血压 镇肝熄风汤 苯磺酸氨氯地平片 随机平行对照研究 

分 类 号：R259[医药卫生—中西医结合] R289.5[医药卫生—中医内科学]