不同产地延胡索饮片炮制前后有效成分含量的测定  

Determination of Main Active Components in Crude and Processed Corydalis Rhizoma Samples from Different Habitats

作　　者：马月光[1,2] 岳显可[2] 曹岗[2] 李进[3] 葛卫红[2] 

机构地区：[1]杭州市第一人民医院,浙江杭州310006 [2]浙江中医药大学,浙江杭州310053 [3]浙江大学医学院附属第一医院,浙江杭州310003

出　　处：《中药材》2013年第11期1754-1758,共5页Journal of Chinese Medicinal Materials

基　　金：浙江省中医药科学研究基金计划(2011ZB101)

摘　　要：目的：比较不同产地延胡索生品和炮制品中延胡索乙素、含水量及醇溶性浸出物的含量。方法：将14批不同产地的延胡索生品，按照中国药典醋煮法进行炮制。采用高效液相色谱法测定生品和炮制品中延胡索乙素的含量，并对含水量及醇溶性浸出物的含量进行考察。结果：14批延胡索饮片生品的水分含量、醇溶性浸出物及延胡索乙素的含量分别在12．8％～14．8％、16．5％-19．6％和0．043％～0．075％；延胡索经醋煮后，水分含量、醇溶性浸出物及延胡索乙素的含量分别在7．58％-11．7％、17．8％-23．5％和0．046％～0．079％。结论：由于各地栽培延胡索土壤、气候等差异，不同产地延胡索炮制前后延胡索乙素、含水量及醇溶性浸出物的含量有所不同。Objective ：To compare the content of water, ethanol soluble extracts and tetrahydropalmatine in crude and processed Corydalis Rhizoma samples from different habitats. Methods：Corydalis Rhizoma was processed according to the optimum processing of the Chinese Pharmacopoeia （2010 edition） , and then, the difference of the content of water, ethanol soluble extracts and tetrahydropalma- tine in crude and processed Corydalis Rhizoma samples were analyzed and compared. Results：From 14 different batches of Corydalis Rhizoma studies,the content of water, ethanol soluble extracts and tetrahydropalmatine in crude Corydalis Rhizoma was 12. 8% 14. 8% , 16. 5% ~ 19.6% and 0. 043% -0. 075% ,respectively; As for Corydalis Rhizoma after processing with vinegar,the content of water, ethanol soluble extracts and tetrahydropalmatine was 7. 58% ~ 11.7%, 17.8% - 23.5 % and 0. 046% - 0. 079%, respectively. Conclusion ： The content of water, ethanol soluble extracts and tetrabydropalmatine varies slightly in the same type of samples from different habitats, which might be due to the difference in soil and climate in each habitat.

关 键 词：高效液相色谱法 延胡索 延胡索乙素 炮制 

分 类 号：R283.1[医药卫生—中药学]