莪术油明胶微球剂的含量测定  

Determination of Zedoary turmeric oil gelatin microspheres

作　　者：邓嵘[1] 陈济民[1] 高声传[2] 丁懿 徐海达 

机构地区：[1]沈阳药科大学药学系,辽宁沈阳110015 [2]沈阳军区总医院,辽宁沈阳110015

出　　处：《中国医院药学杂志》2001年第2期79-81,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的 :研究莪术油明胶微球的含量测定方法。方法 :莪术油明胶微球用胰酶 超声法消解 ,硫酸 香草醛显色后 ,用可见 分光光度法进行测定。结果 :胰酶的用量 ,超声时间 ,消解时间 ,对测定均有影响。结论 :所建立的方法准确 ,可靠 ,适用于莪术油明胶微球剂的含量测定。OBJECTIVE:To study a method for the determination of Zedoary turmeric oil gelatin microspheres (ZTO-GMS).METHODS:ZTO-GMS was degraded by the pancreatin and supersonic and then colored by sulfuric acid-vanillin reagent.The absorbance was measured by visible-spectophotometry at 520 nm.RESULTS:The amount of pancreatin,the time of supersonic,and the time of degradation had influences on the determination.CONCLUSIONS:The method was accuracy,reproducible,reliable and suitable for load content determination of ZTO-GMS.

关 键 词：莪术油 明胶 微球 莪术醇 分光光度法 

分 类 号：R927.2[医药卫生—药学]