维生素B_1咀嚼片的制备及质量控制  

Preparation and Quality Control of Vitamin B_1 Chewable Tablets

作　　者：李威[1] 张睿琦 揭晶[1] 

机构地区：[1]武汉生物工程学院制药工程系,湖北武汉430415

出　　处：《中国医药指南》2014年第5期1-2,4,共3页Guide of China Medicine

基　　金：湖北省自然科学基金项目(项目编号2012FFB05201);2012年度湖北省高等学校青年教师深入企业行动计划项目(XD2012501)

摘　　要：目的通过对维生素B1咀嚼片辅料及其配比的研究,探讨出口感适宜、风味独特的处方工艺。方法以口感和组织状态等为指标,通过正交试验对维生素B1咀嚼片的辅料及配比进行考察,筛选最佳处方。结果通过正交试验确定最佳辅料用量为乳糖40%,柠檬酸10%,甜橙粉15%。结论对所制备的维生素B1咀嚼片进行质量检查,结果表明该产品口感良好、色泽均匀、硬度适宜,符合相关要求。Objective To study chewable accessories of vitamin B1 and its ratio to explore export suitable sense, the unique flavor of the prescription process. Methods The taste and organization of the state as an index to inspect the accessories and the ratio of the chewable tablet of vitamin B1 by orthogonal experiments, screening the best prescription. Results The orthogonal test to determine the amount of the best accessories as follows, 40%lactose, citric acid 10%, orange powder15%. Conclusion For the preparation of vitamin B1 chewable quality inspection, the results indicate that the product tastes good, uniform color and appropriate hardness, and meet the relevant requirements.

关 键 词：维生素B1 咀嚼片 质量控制 正交试验 VITAMIN B1 

分 类 号：R944.4[医药卫生—药剂学]