原发性高血压患者血压变异性的临床观察  

Clinical observation of blood pressure variability in patients with primary hypertension

作　　者：曹萍[1] 熊世熙[1] 周毅[1] 李军[1] 农雯[1] 宋长杰[1] 任江华[1] 曹茂银[1] 王瑞英[1] 

机构地区：[1]湖北医科大学附属第二医院心内科,武汉430071

出　　处：《临床心血管病杂志》2000年第12期531-533,共3页Journal of Clinical Cardiology

摘　　要：目的 :探讨原发性高血压 (EH)患者血压变异性与靶器官损害、血压增高的程度及年龄、性别的关系。方法 :对 480例 EH患者及 2 0 0例正常人 (对照组 )进行 2 4h动态血压监测 ,以测得的血压标准差作为血压变异性指标。结果 :EH组血压变异性明显大于对照组 ; 期 EH患者血压变异性明显大于 期及 期患者 ; 、 期之间血压变异性无明显差异 ;对照组及 EH组各组中男女性别之间血压变异性无显著性差异 ;EH组血压变异性随血压水平的增加而逐渐增大 ,年龄≤ 6 0岁者 ,其血压变异性随年龄的增加而增大 ,年龄 >6 0岁者 ,其血压变异性不再继续增加。结论 :EH患者血压变异性明显增加 ,且靶器官损害越重 ,血压值越高 ,在一定范围内年龄越大则血压变异性越大。Objective:To observe the relationship between blood pressure ( BP) variability and the target organ damage, the extent of BP increasing, age, and gender in patients with primary hypertension. Method:200 normal controls and 480 patients with primary hypertension were undergone 24 hours ambulatory blood pressure monitoring. The BP variability (BPV) was determined by standard deviation (s) from mean blood pressure during the 24 hours.Result:BPV in patients with primary hypertension was higher than that in normal controls (P< 0.01 ). BPV in patients with stageⅢ primary hypertension was higher than that in those with stageⅠand Ⅱ ( P< 0.01 ), but no difference was found between thal in stageⅠand Ⅱ. There was no significance of BPV between males and females in both normal controls and patients (all P> 0.05 ). BPV increased with age in patients less than 60 years old, but did not in those more than 60 years old.Conclusion:Patients with primary hypertension have increased BPV.Furthermore,the BPV increase with the extent of target organ damage,BP value and,to some extent,the age of the patients.

关 键 词：原发性高血压 血压变异性 靶器官损害 

分 类 号：R544.1[医药卫生—心血管疾病]