运用虫类药治疗类风湿关节炎的用药规律研究  

Research on Medication Rules of Insect drugs for Treatment of Rheumatoid Arthritis

作　　者：陈雷鸣[1] 包洁[1] 谢志军[1] 范永升[1] 

机构地区：[1]浙江中医药大学,浙江杭州310053

出　　处：《中华中医药学刊》2014年第3期593-595,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省重点科技创新团队计划项目(2009R50042-002)

摘　　要：目的:探讨运用虫类药治疗类风湿性关节炎的中药用药规律。方法:收集2000—2012年中医治疗类风湿关节炎的文献,检索出其中含虫类药的复方354首,建立数据库,用统计软件进行分析。结果:354首治疗类风湿关节炎的含虫类药复方中,涉及中药211味,累计使用4767次;其中虫类药33味,累计使用844次,使用最多的虫类药为全蝎、乌梢蛇、蜈蚣、地龙等;祛风湿药、补益药、活血化瘀药、清热药、解表药、平肝熄风药等6类药物累计使用90.59%;所用中药四气为温、平者占68.98%,五味为辛、甘、苦者占87.67%,归肝、脾、肾经者占57.94%。结论:治疗类风湿关节炎多运用虫类药搜风剔邪、化瘀通络,扶正祛邪兼顾,药物四气以温平为主,五味以辛甘苦居多,归经多归肝脾肾经。Objective：To investigate the medication rules of insect drugs for the treatment of rheumatoid arthritis （RA）. Methods： The literatures for the treatment of RA in traditional Chinese medicine from 2000 to 2012 were collect- ed. 354 prescriptions containing insect drugs were retrieved to establish a database, and were analyzed with statistical software. Results ： 211 kinds of Chinese traditional herbs were included in 354 prescriptions containing insect drugs for the treatment of RA, and used for 4767 times altogether in the prescriptions, including 33 kinds of insect drugs which were used 844 times. The high frequently- used insect drugs were scorpio, zaocys, centipede and pheretima. The using fre- queficy of 6 major kinds of drugs （drugs for removing wind and dampness, invigorating and nourishing, promoting blood circulation and removing stasis, clearing heat, relieving exterior syndrome, calming liver and suppressing wind） accoun- ted for 90.59%. From the perspective of the tropism of taste, drugs with warm and moderate nature accounted for 68.98% ; drugs with pungent, sweet, bitter tastes accounted for 87.67% ;drugs for liver, spleen, kidney channels accoun- ted for 57.94%. Conclusion： Insect drugs are used a lot to dispelling pathogen and dredging collaterals to treat RA, com- bined with strengthening body resistance and eliminating pathogenic factors. Most of the drugs are with warm and moderate nature and pungent, sweet and bitter tastes;and the channel tropism is mainly for the liver, spleen and kidney channels.

关 键 词：虫类药 类风湿关节炎 用药规律 

分 类 号：R593.22[医药卫生—内科学]