痰热清与头孢美唑联合治疗老年肺部感染疗效分析  

Clinical observation of Tanreqing Combined with Cefmetazole Sodium in Treatment of Pulmonary Infection

作　　者：周光耀[1] 金玲湘[1] 林巍[1] 诸葛璐[1] 潘陈为[1] 郑毅[1] 

机构地区：[1]温州医科大学附属第二医院感染内科,浙江温州325027

出　　处：《中华中医药学刊》2014年第3期622-624,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：温州市科技局基金项目(Y20090296)

摘　　要：目的:探讨痰热清与头孢美唑联合治疗老年肺部感染的临床疗效。方法:本研究于2011年2月—2013年2月通过随机、对照、前瞻的临床研究,将在温州医科大学附属第二医院住院接受治疗的64例老年肺部感染患者按照随机数字表法随机分为研究组和对照组,其中研究组采用痰热清与头孢美唑联合治疗,而对照组则仅采用头孢美唑单独治疗,比较两组患者的临床治疗效果、临床症状缓解时间、体温及x线摄片恢复正常时间。结果:研究组患者中显效13例,有效16例,治疗的总有效率达90.62%;对照组患者中显效10例,有效14例,治疗的总有效率为75.00%;经统计分析发现研究组的总有效率(90.62%)明显高于对照组(75.00%),且差异具有统计学意义(χ2=4.02,P<0.05)。研究组患者的症状缓解时间、体温及X线胸片恢复正常时间均较对照组明显缩短,且差异具有统计学意义(t=6.78、4.89、5.22,P<0.05)。研究组的不良反应总发生率(9.38%)与对照组(12.50%)相比较无明显差异(χ2=0.16,P>0.05)。结论:痰热清与头孢美唑联合治疗老年肺部感染的总有效率明显优于单独采用头孢美唑,且可以明显缩短临床症状缓解时间、体温恢复正常时间及X线胸片恢复正常时间,安全可靠,值得临床推广应用。Objective：To investigate the clinical effect of Tanreqing combined with cefmetazole sodium in the treatment of pulmonary infection. Methods ： From February 2011 to February 2013, 64 cases of senile pulmonary infection patients were randomly divided into study group and control group at The 2nd Affiliated Hospital of Wenzhou Medical University by con- trolled, prospective clinical study. The study group was treated with Tanreqing and cefmetazole sodium while the control group only treated with cefmetazole sodium alone. The clinical symptoms of the two groups, the clinical treatment effect, response time, temperature and X -ray recovery time were compared between the two groups. Results：13 cases in the study group were markedly effective, 16 cases were effective, and the total effective rate of treatment was 90.62%. 10 cases of control group were markedly effective, effective in 14 cases, and the total effective rate of treatment was 75%. Statistical analysis found that the total effective of the study group （90.62%） was significantly higher than that of the control group （75%）, and the difference had statistical significance （Xz = 4.02 ,P 〈 0.05 ）. The study group patients＂ symptoms time, temperature and X- ray recovery time were significantly shorter than those of the control group and the difference had statistical significance （t = 6.78,4.89,5.22, P 〈 O. 05 ）. The total incidence rate of adverse reactions in the study group （9.38%） had no significant difference comparing with that of the control group （ 12.50% ） （ X2 =0. 16, P 〉 0.05 ）. Conclusion：The total efficiency of Tanreqing combined with cefmctazole sodium in the treatment of senile em- physema infection is obviously better than the single use of cefmetazole sodium and it can significantly shorten the time of clinical symptoms, body temperature returned to normal level and X - ray recovery time. It is safe and reliable and is worthy of clinical application.

关 键 词：痰热清 头孢美唑 老年 肺部感染 

分 类 号：R563.1[医药卫生—呼吸系统]