2012年北京市石景山区疑似预防接种异常反应监测分析  

Adverse events following immunization in Shijingshan district,Beijing,2012

作　　者：郭舫茹[1] 吴劲[1] 杨咸枝[1] 杨娜[1] 李敏[1] 

机构地区：[1]北京市石景山区疾病预防控制中心,北京100043

出　　处：《疾病监测》2014年第1期62-65,共4页Disease Surveillance

摘　　要：目的分析北京市石景山区2012年疑似预防接种异常反应(adverse events following immunization,AEFI)的发生情况,评价AEFI监测系统运转情况。方法采用描述性方法对相关指标进行流行病学分析。结果 2012年共报告AEFI 45例,报告发生率17.02/10万,涉及14种疫苗,无细胞百白破疫苗AEFI报告发生数居首位(13例,占28.89%),7价肺炎报告发生率最高,为116.91/10万。反应类型中一般反应占53.33%(全部是发热/红肿/硬结)、异常反应28.89%(皮疹占85%)、偶合症17.78%。病例主要发生在小年龄段人群(≤2岁发生数占75.56%)。发生时间主要集中在5-10月(64%),多在接种后1 d内发生(95.56%)。结论石景山区AEFI监测的完整性和敏感性比较高,但仍需要加强AEFI监测工作,规范预防接种操作,严格掌握禁忌证,减少AEFI发生。Objective To analyze the adverse events following immunization （AEFI） in Shijingshan district of Beijing in 2012 and evaluate the performance of AEFI surveillance system. Methods Descriptive epidemiological analysis was conducted on the incidence data of AEFI in Beijing during this period. Result A total of 45 AEFI were reported, the incidence rate was 17. 02/1akh, Fourteen kinds of vaccines were involved. The cases number caused by diphtheria-tetanus-acellular-pertussis vaccine （DTaP） were highest （13, 28.89% ） , while the incidence of cases caused by pneumococcal conjugate vaccine against 7 pneumococcal serotypes （PCV7） was highest （116. 91/1akh）. In the classification of AEFI cases, 53.33% were general reactions, 28.89% were abnormal reactions and 17.78% were coincidental cases. Up to 75.56% of the cases were children aged ：!S;2 years, the cases mainly occurred between MayOctober and 95. 56% of the cases occurred within 1 day after vaccination. Conclusion The sensitivity and completeness of AEFI surveillance in Shijingshan were well, but still needed improvement. To reduce the AEFI, it is necessary to conduct standard vaccination and distinguish contraindications.

关 键 词：疑似预防接种异常反应 疫苗 监测 

分 类 号：R186[医药卫生—流行病学]