我国小鹅瘟研究进展及成就  

Gosling plague research progress and achievements in China

作　　者：金文杰[1] 吕亚楠[1] 王芳[2] 朱良全[2] 秦爱建[1] 丁家波[2] 

机构地区：[1]扬州大学兽医学院教育部禽类预防医学重点实验室江苏省动物重要疫病与人兽共患病防控协同创新中心,江苏扬州225009 [2]中国兽医药品监察所,北京100081

出　　处：《微生物学通报》2014年第3期504-510,共7页Microbiology China

基　　金：国家公益性行业(农业)专项项目(No.201003012);科技基础性工作专项项目(No.2008FY130100);江苏高校优势学科建设工程资助项目(PAPD)

摘　　要：小鹅瘟是导致雏鹅死亡的常见疾病之一,可造成巨大经济损失,严重危害养鹅业的发展。为了科学认识和积极防控小鹅瘟,我国同行进行了长期不懈的研究,取得了一系列原创性成果。在全世界率先发现并鉴定了小鹅瘟病毒,并对其变异特点进行了遗传进化分析,基本调研清楚了小鹅瘟在我国的发生区域和流行规律。在传统检测技术的基础上,引入免疫学技术和分子生物学技术,建立了一系列快速检测新方法;研制成功高免血清、种鹅用弱毒疫苗、雏鹅用弱毒疫苗和细胞适应弱毒株培育的新型疫苗,使我国小鹅瘟得到了有效的控制。这些成果和进展为我国小鹅瘟的研究与防治奠定了基础。Gosling plague is one of the most common diseases with high mortality in gosling, which could induce huge economic losses and cause serious damage to the development of goose industry. In order to improve the level of scientific understanding, disease prevention and control on gosling plague, the peers performed a lot researches, with the long-term perseverance in our country and ob- tained a series groundbreaking achievements. Gosling plague and its pathogen goose parvovirus （GPV） were first discovered and identified by Dingyi Fang in the world. The variation characteristics of the genetic evolution of GPV were analyzed and the distribution area and epidemiology situation of the Gosling plague in China were investigated preliminarily. As well, on the basis of traditional testing methods, together with the modem immunology and molecular biology technique, a series of rapid diagnostic methods were established. Furthermore the high titer serum, attenuated vaccines for goslings and adult geese were successfully developed to effective controlling of this disease. And some cell-adapted GPV strains were successfully obtained and further applied in clinic, which pro- vided a new vaccine candidate for gosling plague control. All the achievements and progress above lay a good foundation for the gosling plague prevention and control.

关 键 词：小鹅瘟 发现 防治方法 检测技术 

分 类 号：S858.33[农业科学—临床兽医学]