纯水中有氧条件下Pd/C催化的无配体Suzuki反应(英文)  

Pd/C-catalyzed ligand-free and aerobic Suzuki reaction in water

作　　者：饶小峰[1] 刘春[1] 张义霞[1] 高占明[1] 金子林[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,辽宁大连116024

出　　处：《催化学报》2014年第3期357-361,共5页

基　　金：supported by the National Natural Science Foundation of China (21276043);the Ministry of Education Program for New Century Excellent Talents in University (NCET-10-0283)~~

摘　　要：报道一种在纯水中Pd/C催化的高效Suzuki反应体系,该体系无需除氧,且无外加配体和添加剂,底物普适性广泛,含有亲水或疏水基团的溴代芳烃都能被高效活化.此外,对部分杂环芳烃与芳基硼酸的偶联反应也有较好的催化效果.该催化剂可高效循环使用三次,且性能无明显下降.A general and efficient catalytic system for Pd/C-catalyzed ligand-free aerobic Suzuki cross-coupling reactions was developed. The reaction tolerated a wide range of aryl bromides with a hydrophilic group or a hydrophobic group without any additives in water. Moreover, the catalytic system was successfully extended to the cross-couplings of heteroaryl halides with various arylboronic acids. The Pd/C catalyst could be reused three times without significant loss of catalytic activity.

关 键 词：SUZUKI反应 钯 碳 无配体 二异丙胺 联芳化合物 

分 类 号：O643.32[理学—物理化学]