用聚(L-蛋氨酸)/纳米金修饰玻碳电极同时灵敏检测多巴胺和尿酸(英文)  

Simultaneous and sensitive detection of dopamine and uric acid using a poly(L-methionine)/gold nanoparticle-modified glassy carbon electrode

作　　者：Reza Ojani Jahan-Bakhsh Raoof Ali Asghar Maleki Saeid Safshekan 

机构地区：[1]Electroanalytical Chemistry Research Laboratory,Faculty of Chemistry,University of Mazandaran

出　　处：《催化学报》2014年第3期423-429,共7页

基　　金：supported by Iranian Nanotechnology Society

摘　　要：A novel electrochemical sensor was fabricated by electrodeposition of gold nanoparticles on a poly(L-methionine)(PMT)-modified glassy carbon electrode(GCE) to form a nano-Au/PMT composite-modified GCE(nano-Au/PMT/GCE).Scanning electron microscopy and electrochemical techniques were used to characterize the composite electrode.The modified electrode exhibited considerable electrocatalytic activity towards the oxidation of dopamine(DA) and uric acid(UA) in phosphate buffer solution(pH = 7.00).Differential pulse voltammetry revealed that the electrocatalytic oxidation currents of DA and UA were linearly related to concentration over the range of 5.0 ×10–8 to 10–6 mol/L for DA and 7.0 × 10–8 to 10–6 mol/L for UA.The detection limits were 3.7 × 10–8mol/L for DA and 4.5 × 10–8 mol/L for UA at a signal-to-noise ratio of 3.According to our experimental results,nano-Au/PMT/GCE can be used as a sensitive and selective sensor for simultaneous determination of DA and UA.A novel electrochemical sensor was fabricated by electrodeposition of gold nanoparticles on a poly（L-methionine） （PMT）-modified glassy carbon electrode （GCE） to form a nano-Au/PMT compo- site-modified GCE （nano-Au/PMT/GCE）. Scanning electron microscopy and electrochemical tech- niques were used to characterize the composite electrode. The modified electrode exhibited con- siderable electrocatalytic activity towards the oxidation of dopamine （DA） and uric acid （UA） in phosphate buffer solution （pH = 7.00）. Differential pulse voltammetry revealed that the electrocat- alytic oxidation currents of DA and UA were linearly related to concentration over the range of 5.0 × 10^-8 to 10^-6 mol/L for DA and 7.0 × 10^-8 to 10^-6 mol/L for UA. The detection limits were 3.7 × 10^-8 mol/L for DA and 4.5 × 10^-8 mol/L for UA at a signal-to-noise ratio of 3. According to our experi- mental results, nano-Au/PMT/GCE can be used as a sensitive and selective sensor for simultaneous determination of DA and UA.

关 键 词：L-蛋氨酸 玻碳电极 多巴胺 金纳米颗粒 尿酸 电化学传感器 扫描电子显微镜 磷酸盐缓冲溶液 

分 类 号：O657.1[理学—分析化学] TQ463.27[理学—化学]