高效可回收多相催化剂SiO_2-Cu_2O催化伯胺和仲胺苄基化反应(英文)  

SiO_2-Cu_2O:An efficient and recyclable heterogeneous catalyst for N-benzylation of primary and secondary amines

作　　者：Manjulla Gupta Satya Paul Rajive Gupta 

机构地区：[1]Department of Chemistry,University of Jammu

出　　处：《催化学报》2014年第3期444-450,共7页

基　　金：UGC,New Delhi for financial support to purchase FTIR;awarding Major Research Project (F 41-281/2012 (SR));Prof.R.K.Bamezai,Department of Chemistry,University of Jammu for recording TGA

摘　　要：A mild,effective,and selective procedure is reported for the mono N-benzylation and N,N-dibenzylation of primary amines as well as mono N-benzylation of secondary amines using silicasupported copper(I) oxide in water.The silica-supported Cu2O was generated in situ by the reaction of Fehling solution and glucose at 100 °C onto activated silica.The catalyst was filtered,washed with water,and oven-dried,and was characterized by Fourier transform infrared spectroscopy,thermogravimetric analysis,scanning electron microscopy,transmission electron microscopy,and atomic absorption spectroscopy.The prepared Cu2O-SiO2 was found to be thermally stable up to 325 °C.The copper was uniformly distributed onto the surface of the silica,and the mean particle diameter was 7 nm.The catalyst served as a selective heterogenous catalyst for the N-benzylation of primary and secondary amines.The catalyst is recyclable and was used effectively upto fifth run without a significant loss of catalytic activity.Various reaction solvents including water,acetonitrile,and toluene were screened for N-benzylation of amines,and the success of the aqueous system highlights the low environmental impact of the procedure.A mild, effective, and selective procedure is reported for the mono N-benzylation and N,N-diben- zylation of primary amines as well as mono N-benzylation of secondary amines using sili- ca-supported copper（1） oxide in water. The silica-supported Cu2O was generated in situ by the reac- tion of Fehling solution and glucose at 100℃ onto activated silica. The catalyst was filtered, washed with water, and oven-dried, and was characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, scanning electron microscopy, transmission electron microscopy, and atomic absorption spectroscopy. The prepared Cu2O-SiO2 was found to be thermally stable up to 325 ℃. The copper was uniformly distributed onto the surface of the silica, and the mean particle diameter was 7 nm. The catalyst served as a selective heterogenous catalyst for the N-benzylation of primary and secondary amines. The catalyst is recyclable and was used effectively upto fifth run without a significant loss of catalytic activity. Various reaction solvents including water, acetonitrile, and toluene were screened for N-benzylation of amines, and the success of the aqueous system highlights the low environmental impact of the procedure.

关 键 词：非均相催化剂 二氧化硅 氧化亚铜 可回收 傅立叶变换红外光谱法 二级胺 扫描电子显微镜 原子吸收光谱法 

分 类 号：O643.32[理学—物理化学]