2007年至2012年我院827例药品不良反应报告分析  

Analysis on 827 Cases of ADR Reports from 2007 to 2012

作　　者：张先芬 周颖[1] 周国民[1] 

机构地区：[1]四川省内江市第二人民医院,四川内江641100

出　　处：《中国药业》2014年第6期52-53,共2页China Pharmaceuticals

摘　　要：目的探讨医院药品不良反应(ADR)发生的一般规律和特点,为临床合理用药提供参考。方法收集医院2007年至2012年827例ADR报告进行分类统计、分析。结果报告者比例为医师62.15%,护士16.81%,药师21.04%;新的和严重的ADR分别是106例(12.82%)和79例(9.55%);静脉滴注给药引起的ADR为645例(77.99%);涉及药品18个大类149种,其中排序首位的是抗感染药物402例(48.61%),有56种药品;皮肤及其附件损害发生率最高,占总病例数的35.91%。结论应全方位加强ADR监测工作,以减少和避免药品不良反应发生。Objective To investigate the general rule and characteristics of adverse drug reaction （ADR） occurrence to provide reference for the clinical rational drug use. Methods 827 cases of ADR report in our hospital during 2007-2012 were collected and performed the classification statistics and analysis. Results Among the reporters,physicians accounted for 62. 15%, nurses for 16.81% and phar- macists for 21.04% ;new and serious ADR were 106 eases （12.82%） and 79 cases （9.55%） respectively;645 eases of ADR were caused by intravenous drip （77.99%）;the involved drugs were 149 varieties in 18 categories,in which the ranking first was anti-in- fection drugs（402 cases,48. 61% ）,56 kinds of drugs;skin and its appendages had the highest occurrence rate of ADR,whieh accounted for 35.91% of the total number of cases. Conclusion ADR monitoring should be comprehensively strengthened to reduce and avoid the occurrence of ADR.

关 键 词：药品不良反应 监测 合理用药 

分 类 号：R969.3[医药卫生—药理学] R954[医药卫生—药学]