垂体功能减退症并渗透性脱髓鞘综合征2例报告并文献复习  

Case report of osmotic demyelination syndrome in two patients with hypopituitarism during treatment and literature review

作　　者：游志清[1] 郎红梅[1] 刘君静[1] 程莹[1] 郭蔚[1] 艾智华[1] 万勇[1] 李宁娜[1] 张扬[1] 

机构地区：[1]中国人民解放军成都军区总医院内分泌科, 成都610083

出　　处：《国际内分泌代谢杂志》2014年第2期141-143,共3页International Journal of Endocrinology and Metabolism

摘　　要：垂体功能减退症患者常有慢性低钠血症,治疗中出现渗透性脱髓鞘综合征（ODS）的报道极少.本文报道2例垂体功能减退患者在治疗过程中出现ODS,分析其原因,并对文献进行复习.过快纠正低血钠会导致ODS的发生,预防ODS的发生是关键,目前尚无ODS的特效治疗,需综合治疗.Patients with hypopituitarism often develop chronic hyponatremia,and osmotic demyelination syndrome（ODS） is seldom happened during the treatment.Two cases with hypopituitarism occurred ODS were reported here and the reasons were analyzed.Overly rapid correction of chronic hyponatremia can lead to ODS.The prevention of ODS is the key.Currently,there is not special treatment,and combining treatment is needed.

关 键 词：渗透性脱髓鞘综合征 垂体功能减退症 低钠血症 

分 类 号：R584.2[医药卫生—内分泌] R744.5[医药卫生—内科学]