糖尿病患者腰围身高比值与2型糖尿病肾病的相关性  被引量:2

Correlation between the waist-to-height ratio and diabetic nephropathy in patients with type 2 diabetes mellitus

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作  者:顾文元[1] 赵伟[2] 郑晓[2] 张宏[2] 

机构地区:[1]天津中医药大学第二附属医院急症科,天津300150 [2]天津医科大学代谢病医院内分泌研究所,卫生部激素与发育重点实验室

出  处:《中国慢性病预防与控制》2014年第1期13-15,共3页Chinese Journal of Prevention and Control of Chronic Diseases

摘  要:目的探讨糖尿病患者腰围身高比值(WHtR)与2型糖尿病肾病的相关性。方法选择426例2型糖尿病患者,根据有无并发糖尿病肾病分为糖尿病肾病组(DN)103例和非糖尿病肾病组(NDN)323例。比较两组2型糖尿病患者的血压、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、糖化血红蛋白及WHtR。logistic回归分析WHtR与糖尿病肾病的相关性。结果 DN组患者病程、收缩压、TG、WHtR分别为(8.7±7.6)年、(140±20)mmHg、(2.59±2.11)mmol/L、0.58±0.06,较NDN组[分别为(6.6±6.2)年、(131±17)mmHg、(2.01±1.69)mmol/L、0.55±0.06]明显增高,差异均有统计学意义(P<0.05,P<0.01),调整了性别、年龄、糖尿病病程、血压、血脂谱、糖化血红蛋白后,WHtR与糖尿病肾病明显正相关(OR=594.899,95%CI:8.731~40 534.869)。结论 WHtR是2型糖尿病肾病的独立危险因素,积极防治肥胖可能有助于糖尿病肾病的防治。Objective To explore the correlation between the waist-to-height ratio (WHtR) and diabetic nephropathy in patients with type 2 diabetes mellitus (T2DM). Methods 426 patients with T2DM were divide into diabetic nephropathy (DN) group (103 eases) and non diabetic nephropathy (NDN) group (323 eases). Blood pressure, blood lipids, HbA^c levels and WHtR were compared between two groups. Logistic regression was used to analysis the correlation between WHtR and diabetic nephropathy. Results As compared with NDN group [(6.6±6.2) years, (131±17) mmHg, (2.01±1.69) retool/L, 0.55±0.06, respectively], the diabetic duration [(8.7±7.6) years], systolic blood pressure (SBP) [(140±20) mmHg], triglyeeride (TG) [(2.59±2.11 ) mmol/L] and WHtR (0.58±0.06) in DN group increased significantly (P〈0.05, P〈0.01 ). After adjusting the sex, age, duration, blood pressure, blood lipids and HbAlc, there was a positive correlation between WHtR and diabetic nephropathy (OR=594.899,95%CI: 8.731- 40 534.869). Conclusion WHtR is an independent risk factor of diabetic nephropathy, the prevention and treatment of obesity may be useful for preventing the diabetic nephropathy.

关 键 词:2型糖尿病 糖尿病肾病 腰围身高比 

分 类 号:R587.1[医药卫生—内分泌]

 

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