Highly efficient one-pot synthesis of dihydropyran heterocycles  

作　　者：Mohamed A.Ameen Sara M.Motamed Fathy F.Abdel-latif 

机构地区：[1]Chemistry Department.Faculty of Science,El Minia University

出　　处：《Chinese Chemical Letters》2014年第2期212-214,共3页中国化学快报（英文版）

摘　　要：Diammonium hydrogen phosphate and potassium carbonate-catalyzed one-pot synthesis of 1,4- phenylene-bis（2-amino-4H-pyran-3-carbonitrile and 2-amino-4-aryl-4H-pyran-3-carbonitrile deriva- tives has been achieved by a three-component cyclocondensation of aldehydes, malononitrile, and different nucleophiles in aqueous medium in high yields.Diammonium hydrogen phosphate and potassium carbonate-catalyzed one-pot synthesis of 1,4- phenylene-bis（2-amino-4H-pyran-3-carbonitrile and 2-amino-4-aryl-4H-pyran-3-carbonitrile deriva- tives has been achieved by a three-component cyclocondensation of aldehydes, malononitrile, and different nucleophiles in aqueous medium in high yields.

关 键 词：One pot synthesis Diammonium hydrogen phosphate PYRAN Aqueous media 

分 类 号：TQ253[化学工程—有机化工]