Copper-catalyzed Ullmann-type synthesis of diaryl ethers assisted by salicylaldimine ligands  

作　　者：Cun-Wei Qian Wen-Lin Lv Qian-Shou Zong Mao-Yuan Wang Dong Fang 

机构地区：[1]School of Chemistry and Chemical Engineering,Yancheng Teachers University [2]School of Biological and Chemical Engineering,Jiaxing University

出　　处：《Chinese Chemical Letters》2014年第2期337-340,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China;Key Laboratory of Organic Synthesis of Jiangsu Province for the financial support(Nos.21201147,21302063,KJS1112)

摘　　要：A series of salicylaldimine ligands were designed to promote the copper-catalyzed Ullmann cross- coupling reaction. After a screening process, 2-（（2-isopropylphenylimino）methyl）phenol was found to serve as a good supporting ligand for this reaction. Employing this Schiff-base ligand as a new supporting ligand, the copper-catalyzed coupling reactions of aryl bromides and aryl iodides with various phenols successfully proceeded in good yields under mild conditions. Various diaryl ethers were obtained with excellent yields in dioxane in the presence of K3P04 and a catalytic amount of copper（I） salt.A series of salicylaldimine ligands were designed to promote the copper-catalyzed Ullmann cross- coupling reaction. After a screening process, 2-（（2-isopropylphenylimino）methyl）phenol was found to serve as a good supporting ligand for this reaction. Employing this Schiff-base ligand as a new supporting ligand, the copper-catalyzed coupling reactions of aryl bromides and aryl iodides with various phenols successfully proceeded in good yields under mild conditions. Various diaryl ethers were obtained with excellent yields in dioxane in the presence of K3P04 and a catalytic amount of copper（I） salt.

关 键 词：Copper catalyst Salicylaldimine ligands Ullmann coupling Diaryl ethers 

分 类 号：O643.32[理学—物理化学]