舒神灵胶囊质量标准研究  

Quality Standard for Shushenling Capsules

作　　者：汝秋明 楚云杰[2] 

机构地区：[1]吉林省食品药品检验所,吉林长春130033 [2]长春中医药大学附属医院,吉林长春130021

出　　处：《中国现代中药》2014年第2期144-147,150,共5页Modern Chinese Medicine

摘　　要：目的：建立舒神灵胶囊的质量标准。方法：采用薄层色谱法对该制剂中的丹参、五味子、甘草、人参进行定性鉴别；采用HPLC测定该制剂中五味子的有效成分五味子醇甲的含量。结果：薄层色谱可鉴别出丹参、五味子、甘草、人参的特征斑点，且阴性对照无干扰。HPLC法测定五味子醇甲在0．0407—0．3665μg线性关系良好，平均加样回收率为100．38％，RSD=1．2％（n=6）。结论：该方法简便可靠，专属性强，重现性好，可用于舒神灵胶囊的质量控制。Objective： To establish quality standard for Shushenling Capsules. Methods： Salviae miltiorrhizae Radix et Rhizoma, Schisandrae chinensis Fructus, Glycyrrhizae Radix et Rhizoma, Ginseng Radix et Rhizoma were identified by TLC, and the content of schisandrin in Schisandrae chinensis Fructus was determined by HPLC. Results： TLC could identify Salviae miltiorrhizae Radix et Rhizoma, Schisandrae chinensis Fructus, Glycyrrhizae Radix et Rhizoma, and Ginseng Radix et Rhizoma. schisandrin showed a good linear relationship at a range of 0.040 7 - 0.366 5μg. The average recovery was 100.38% （n = 6） , and RSD was 1. 2 % . Conclusion： The method is simple, accurate, high specificity, and with good repeatability. The method can be used for Shushenling Capsules quality control.

关 键 词：舒神灵胶囊 薄层色谱法 高效液相色谱法 五味子醇甲 质量标准 

分 类 号：R284.1[医药卫生—中药学]