大剂量服用格列美脲、二甲双胍、吡格列酮1例  

Large doses of glimepiride,metformin,pioglitazone one case

作　　者：付红军[1] 吴美慧[1] 高政南[1] 

机构地区：[1]大连市中心医院内分泌科,辽宁大连116033

出　　处：《中国医药科学》2014年第3期160-162,共3页China Medicine And Pharmacy

摘　　要：随着糖尿病患者的逐年增多,降糖药物被广泛的认识和应用,降糖药物的过量应用,可出现诸多副作用。糖尿病患者大剂量服用二甲双胍(格华止)、格列美脲(亚莫利)、吡格列酮(艾汀)后出现急性肾功能衰竭、乳酸酸中毒、消化道出血、脑水肿、呼吸衰竭等一系列并发症,依据药物特性及并发症情况积极选择血液净化治疗及其他抢救措施,成功挽救患者生命,现报道该病例。With diabetes increasing year by year,hypoglycemic drugs are widely recognized and applied,excessive use of hypoglycemic drugs,there may be many side effects.Diabetic patients taking large doses of metformin （glucophage）,glimepiride（amaryl）,pioglitazone（yiting） after acute renal failure,lactic acidosis,gastrointestinal bleeding,cerebral edema,respiratory failure and a series of complications,according to the characteristics and complications of drug positive blood purification therapy and other select rescue measures,successfully saved the lives of patients,are reported in the following cases.

关 键 词：二甲双胍 格列美脲 吡格列酮 乳酸酸中毒 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]