小鼠子宫蜕膜化过程中细胞周期调控相关因子的研究进展  

The Research Progress of Cell Cycle Regulators in Mouse Uterine Decidualization

作　　者：李文萍[1] 贲文锐[1] 李瑞婷[1] 靳方圆[1] 倪华[1] 

机构地区：[1]东北农业大学生命科学学院,哈尔滨150030

出　　处：《中国细胞生物学学报》2014年第3期380-386,共7页Chinese Journal of Cell Biology

基　　金：国家转基因重大专项项目(批准号:2011ZX08007-002)资助的课题~~

摘　　要：多倍性细胞的产生作为小鼠子宫蜕膜化的标志之一,其过程是受到细胞周期调控因子的严格调控的。目前对于细胞周期调控因子在蜕膜过程的研究已经很多,但有一些分子机制尚不明确,该文对近几年来小鼠子宫蜕膜化过程中细胞周期调控因子以及这些因子相互作用的研究做出综述,以期对未来临床医学提供更多理论依据。The formation of polyploidy cells, as one of the remarkable events in mouse decidua, is strictly regulated by the cell cycle regulators. At present, there are many researches about cell cycle regulators in deciduas, but the molecular mechanism is unclear. This paper reviewed the research progress about cell cycle regulators and interaction of these factors in mouse uterine decidualization. These results will provide more theoretical basis for clinical medicine in the future.

关 键 词：细胞周期蛋白 细胞周期依赖性蛋白激酶 细胞周期依赖性蛋白抑制剂 蜕膜细胞 核内复制周期 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]