原发性甲状旁腺功能亢进症的SPECT/CT诊断  

^(99m)Tc-MIBI Planar and SPECT/CT Scintigraphy in Diagnosis of Primary Hyperparathyroidism

作　　者：张连娜[1] 杨芳[1] 冯瑾[1] 

机构地区：[1]北京积水潭医院核医学科

出　　处：《中国医学计算机成像杂志》2014年第1期64-67,共4页Chinese Computed Medical Imaging

摘　　要：目的:探讨99mTc-甲氧基异丁基异腈(MIBI)平面显像及SPECT/CT断层图像融合检查在原发性甲状旁腺功能亢进中定位及定性诊断价值。方法:对31例拟诊为甲旁亢患者行99mTc-MIBI平面显像及SPECT/CT断层图像融合检查,分析两种检查方法的灵敏度。结果:31例患者经临床手术病理均确诊为甲旁亢,其中甲状旁腺腺瘤27例,甲状旁腺增生3例,甲状旁腺癌1例。99mTc-MIBI平面显像及SPECT/CT断层图像融合检查的敏感性分别为87.1%和96.8%,二者差异有显著性意义(P<0.05)。结论:99mTc-MIBI SPECT/CT融合显像是有效的探测甲状旁腺病变的影像学方法,在PHPT患者的定位诊断中具有较高的临床价值。Purpose： To evaluate the clinical value of 99mTc-MIBI planar and SPECT/CT scintigraphy imaging in primary hyperparathyroidism （PHPT）. Methods： This study included 31 patients with PHPT properly diagnosed. There were 27 cases of parathyroid adenomas （including 6 ectopic lesions）, 3 cases of parathyroid cysts and 1 case of parathyroid carcinoma. Preoperative 99mTc-MIBI scintigraphy were done in all cases and SPECT/CT scintigraphy were done in 4 cases. The sensitivity of them was calculated and compared. Results： The sensitivity of 99mTc-MIBI planar scintigraphy in detecting lesions of parathyroid was 87.1%. The sensitivity was increased to 96.8% after the SPECT/CT seintigraphy was done, the diagnostic sensitivity was higher than that of planar scintigraphy （P〈0.05）. Conclusion： 99mTc-MIBI SPECT / CT imaging is an effective method for detection of parathyroid lesions, and with high clinical application value in the diagnosis of patients with PHPT.

关 键 词：原发性甲状旁腺功能亢进症 99m锝 甲氧基异丁基异腈 单光子发射型计算机断层显像 计算机断层扫描 

分 类 号：R816.6[医药卫生—放射医学]