1162例2型糖尿病患者慢性并发症筛查结果分析  

A Survey on Chronic Complications of 1 162 Cases of Type 2 Diabetes

作　　者：刘颖[1] 梅伟群[1] 李志琛[1] 高诚明[1] 陈建斌[1] 

机构地区：[1]解放军第117医院机场路院区内分泌科,浙江杭州310004

出　　处：《武汉大学学报（医学版）》2014年第2期222-227,共6页Medical Journal of Wuhan University

基　　金：浙江省公益性技术应用研究计划项目(编号:2012C33120)

摘　　要：目的:分析在我院内分泌科筛查的1 162例2型糖尿病患者各种慢性并发症的发生情况。方法:糖尿病患者在初次来我院内分泌科就诊时均进行糖尿病慢性并发症筛查和既往筛查史的调查,区分既往主动和被动筛查史,统计和分析2005-2012年纳入的1 162例2型糖尿病患者各种慢性并发症的患病率、本筛查中的发现率以及既往主动和被动筛查率。结果:2005-2012年,既往总筛查率随年份变化的趋势明显,呈升高态势(趋势卡方值为322.82,P=0.000);按两个年份段相比:2009-2012年份段既往总筛查率和主动筛查率明显高于2005-2008年份段(32.47%比20.13%;14.21%比1.53%);但总体而言,既往总筛查率(均值26.43%)特别是主动筛查率(均值8.41%)不高;各种慢性并发症的患病率从29.35%到86.92%不等,无阳性发现者仅占6.8%;本筛查对各种慢性并发症的发现率从21.43%到68.62%不等,尿微量白蛋白/Cr比值升高的发现率最高,其次为糖尿病性视网膜病变。结论:糖尿病慢性并发症的高发病率与目前较低的筛查率形成明显的对比,主动筛查是早期发现各种慢性并发症的必要手段。应加强糖尿病患者主动筛查的意识,医院及相关部门应开展规范的筛查管理,以降低慢性并发症的危害。Objective： To survey on chronic complications of 1162 patients with type 2 diabetes from an endocrinologist screening. Methods：History of screening and chronic complications of patients with type 2 diabetes who visit firstly to our hospital were screened, then the history of active and passive screening were distinguished, and the prevalence of chronic complications, discovery rate of screening, and previous active and passive screening rates were analyzed. Results： From 2005 to 2012, previous screening rates was increasing year by year （trend X^2 =322.82, P=0. 000）. In the period of 2009 to 2012, the total screening rate and active screening rate were significantly higher than that respectively in the period of 2005-2008 （32.47% vs 20.13%, 32.47% vs 20.13% ;P〈O.05, respectively）. But on the whole, previous screening rate （average 26.430/oo） and active screening rate （average 8.41%） was not high. Prevalence of all kinds of chronic complications was ranging from 29.35% to 86.92%, and negative discoverer accounted for 6.8%. The screening of all kinds of chronic complications detection rates ranged from 21. 43% to 68.62%, and abnormal rate of urine trace albumin/Cr ratio was most common, followed by diabetic retinopathy. Conclusion. High rate of chronic complications of diabetes and low screening rate exist in the type 2 diabetes risk population, and it suggests that active screening is important for early diagnosing diabetes and preventing complications.

关 键 词：2型糖尿病 糖尿病慢性并发症 筛查 

分 类 号：R587.2[医药卫生—内分泌]