320排CT全脑一站式成像技术对颅内高灌注病灶的诊断价值分析  

Image analysis of intracranial high perfusion lesion by whole brain one-stop imaging technique with 320 detector rows CT

作　　者：杜飞舟[1] 顾明[1] 何次[1] 蒋锐[1] 关静[1] 

机构地区：[1]成都成都军区总医院医学影像科,610083

出　　处：《解放军医学杂志》2014年第3期217-221,共5页Medical Journal of Chinese People's Liberation Army

基　　金：成都军区“十二五”医学科研课题面上项目(C12036)~~

摘　　要：目的利用320排CT一站式成像技术分析颅内高灌注病灶的灌注特征及血管构筑特征,探讨一站式成像技术对颅内病变的临床诊断价值。方法采用320排CT一站式成像技术分析2010年10月-2013年4月成都军区总医院收集的52例颅内高灌注病灶的影像资料,以病变对侧正常脑组织灌注值为对照,分析病灶各灌注参数的y变化特征及血管构筑特征。结果 52例中亚急性期脑梗死16例,动静脉畸形9例,血管瘤7例,脑膜瘤12例,胶质瘤8例。所有病例均表现为血容量图(CBV)和(或)血流量图(CBF)的升高,而平均通过时间(MTT)、达峰时间(TTP)、延迟时间(delay time)等参数变化不一。亚急性脑梗死表现为MTT、TTP、延迟时间延长;动静脉畸形表现为MTT、TTP、延迟时间缩短;血管瘤表现为MTT缩短和TTP、延迟时间延长;脑肿瘤表现为TTP、延迟时间延长,MTT变化不一。血管成像显示所有病例均可见不同程度的血管构筑异常。结论全脑灌注、血管一站式成像分析能够全面反映颅内病灶的灌注特征及血供、微循环变化,有利于指导临床诊治。Objective The perfusion and vascular architecture features were investigated and evaluated by use of one-stop imaging technique with 320 rows CT for exploring the clinical value of one-stop imaging technique in the diagnosis of intracranial lesions. Methods The perfusion parameters and vascular architecture of intracranial high perfusion lesions of 52 patients were collected in General Hospital of Chengdu Command from Oct. 2010 to Apr. 2013, who were examined by one-stop imaging technique with 320 rows CT, were retrospectively analyzed. The perfusion values of normal contralateral cerebral tissue were used as control to analyze the perfusion and vascular architecture features of injured parts. Results Of the 52 patients, there were 16 cases of subacute cerebral infarction, 9 cases of arteriovenous malformation, 7 cases of hemangioma, 12 cases of meningioma, and 8 cases ofglioma. All the patients showed elevated CBV and/or CBF and different changes in mean transit time （MTT）, time to peak （TTP） and delay time （Delay）. In the cases of subacute cerebral infarction, the parameters of MTT, TTP and Delay increased. In the cases of arteriovenous malformation, all the parameters decreased. In the cases of hemangioma, the MTT decreased, while TTP and Delay increased. In the cases of glioma, the TTP and Delay increased, while the change of MTT varied. Meanwhile, abnormality of vascular structures was found in all the cases by CT angiography. Conclusion With whole brain perfusion and one-stop vascular imaging with 320 rows CT, the perfusion characteristics ofintracranial lesions can be revealed completely, including blood supply and microcirculation changes in the lesions, and it may be of benefit in guiding the clinical diagnosis and treatment.

关 键 词：体层摄影术 X线计算机 脑血管造影术 

分 类 号：R814.42[医药卫生—影像医学与核医学]