静脉注射碘克沙醇(270mgI/mL)全身不良反应的临床观察  

Adverse reactions of Iodixanol (270mg I/mL) in coronary CT angiography

作　　者：张保翠[1] 罗晶晶[1] 王霄英[1] 吴静云[1] 张来运 陈卫东[1] 

机构地区：[1]北京大学第一医院医学影像科,北京100034

出　　处：《放射学实践》2014年第3期242-244,共3页Radiologic Practice

摘　　要：目的:观察静脉注射碘克沙醇(270mg I/mL)的全身不良反应。方法:回顾性分析本院2013年1月-9月行冠状动脉CTA检查的824名连续患者的病例资料。观察患者注射碘克沙醇(270mg I/mL)中及注射后1周内出现的全身不良反应及肾脏损害情况。结果:824名患者中有1人出现急性中度全身不良反应,发病率为0.12%;9例出现迟发型全身不良反应,发病率为1.09%;115例血肌酐资料完整的病例中,有8例出现一过性血肌酐增高,其中5例被认为与对比剂无关,3例被诊断为对比剂肾病,发病率为2.61%。上述不良反应均经过一定时间后恢复。结论:静脉注射碘克沙醇(270mg I/mL)是安全的。Objective：To report the adverse reactions related to iodinated contrast medium in patients undergoing cor onary CT angiography using iodixanol （270mg I/mL）. Methods： A total of 824 consecutive patients＇ data undergoing coro nary CTA were analyzed retrospectively. The adverse reactions related to contrast media within 1 week were recorded,inclu ding acute and delayed adverse reactions, and renal impairment. Results：One patient was reported of acute moderate adverse reactions, with incidence of 0.12%（1/824）. Nine patients were reported of delayed adverse reactions, with incidence 1.09 % （9/824）. Three patients were reported of contrast-induced nephropathy, with incidence of 2.61 % （3/115）. Conclusion： Io- dixanol is safe for clinical application.

关 键 词：对比剂 不良反应 对比剂肾病 

分 类 号：R816[医药卫生—放射医学]