120kVp条件下碘克沙醇(270mgI/mL)在冠状动脉CTA检查中的个性化应用研究  

Personalization of contrast media injection in coronary CT angiography with 120kVp and iodixanol(270mg I/mL)

作　　者：周宇[1] 刘建新[1] 王霄英[1] 

机构地区：[1]北京大学第一医院影像科,北京100034

出　　处：《放射学实践》2014年第3期268-271,共4页Radiologic Practice

摘　　要：目的：研究120kVp条件下冠状动脉CTA（CCTA）检查中对比剂的个体化应用的效果。方法：回顾性搜集冠状动脉CTA检查中，个性化注射对比剂的连续患者的资料，共104例，与前期固定给药的连续患者资料进行比较。个性化给药组中，采用碘克沙醇（270mgI／mL），剂量1mL／kg；注射流率根据患者体重设定：％54kg为4．0mL／s，55～64妇为4．5mL／s，65～74蚝为5．0mL／s，〉75kg为5．5mL／S。固定给药组中，采用碘帕醇（370mgI／mL），总量为60mL，注射流率为4．5mL／s。两组病例的cT扫描方案相同。由有经验的影像医师对冠状动脉CTA图像进行主观评价，并对评价结果进行统计分析。测量两组患者右冠状动脉、左冠状动脉前降支、左冠状动脉回旋支近段、中段、远段的CT值，进行统计分析。结果：个性化给药组，平均体重为70．2妇，平均碘剂量为17．68gI／人；固定给药组，平均体重为67．6妇，平均碘剂量为22．2gI／人。两组病例，冠状动脉各节段图像质量均达到临床诊断要求。客观评估：两组病例，所有冠状动脉节段CT值均接近或〉300HU。结论：120kVp条件下，碘克沙醇（270mgI／mL）在CCTA检查中的个性化应用是可行的。此条件下，图像质量可达到临床诊断要求，同时降低对比剂用量，推荐用于肾功能损害高风险的人群。Objective：To investigate the personalization protocol of contrast media injection in coronary CT angiogra phy with 120kVp iodixanol （270mg I/mL）. Methods：Data of consecutive patients were retrospectively collected with com plete contrast media injection records. Totally 104 patients were given contrast media with personalized protocol, tailored to body weight. The data were compared with that of the other group of 104 patients, who were given contrast media with fixed protocol. The image quality of the two groups were analyzed objectively and subjectively. Results：The total iodine de livered in personalized protocol group was much lower than that of the fixed protocol group （average 20% less,P〈0.05）. However,the image quality of the 2 groups were not statistically significant different. The CT values of the coronal vessels were about 300HU. Conclusion：Personalized contrast media injection protocol is feasible in 120kVp coronary CT angiogra phy with iodixanol （270mg I/mL）. It should be recommended to patients with high-risk renal function impairment.

关 键 词：体层摄影术 X线计算机 对比剂 个性化 

分 类 号：R816.2[医药卫生—放射医学]