清肝解毒合健脾益气法治疗肝癌的临床观察  

作　　者：程禹帅 赵冬梅 谭恰 蒋梅[4] 

机构地区：[1]广东省阳江市阳东县人民医院中医肿瘤科,阳东529999 [2]广东省阳江市人民医院,阳江529500 [3]广东省阳江市中西医结合医院,阳江529500 [4]广州中医药大学第一附属医院三肿瘤科,广州510405

出　　处：《北方药学》2014年第3期16-17,共2页Journal of North Pharmacy

摘　　要：目的:探讨清肝解毒合健脾益气法治疗肝癌的临床疗效。方法:清肝解毒合健脾益气法治疗30例肝癌,采用治疗组和对照组对照研究,观察主要症状体征和瘤体的变化、生存情况以及安全性监测。12周后进行客观疗效及不良反应评价。结果:治疗后主要症状体征均有所改善,其中腹胀减轻19例(73.1%),纳差改善16例(24%),肝区疼痛减轻13例(52%),腹水减少8例(47.1%);黄疸不同程度减退8例(29.2%),体力及营养状态改善22例(73.3%)。瘤体变化情况:CR 0例占0%,PR 3例占26.7%,SD 13例占43.3%,PD 14例占46.7%;安全性监测:不良反应较轻,耐受性好。结论:清肝解毒合健脾益气法治疗肝癌效果好,能有效减轻症状,改善患者生存质量。Objective：To explore the clinical effect of Qinggan Jiedu and strengthening the spleen and replenishing qi in the treatment of liver cancer. Methods： Qinggan Jiedu and strengthening the spleen and replenishing qi to treat 30 cases of liver cancer, the group and the control group comparison study of treatment, observation of the changes of main symptoms and signs, and tumor cell survival and security monitoring. Objective evaluation of efficacy and adverse reactions after 12 weeks. Results： after the treatment, the main symptoms and signs were improved, the bloating relieved in 19 cases （73.1%）, loss of appetite improved in 16 cases （24%）, liver pain was relieved in 13 cases （52%）, ascites was decreased in 8 cases （47.1%）; jaundice different extent in 8 cases （29.2%）, physical and nutritional status improved in 22 cases （73.3%）. Tile change of the tumor： 0 cases of CR accounted for 0%, 3 cases of PR accounted for 26.7%, 13cases of SD accounted for 43.3%, 14cases of PD accounted for 46.7%; safety monitoring： mild adverse reactions, good tolerance. Conclusion： Qinggan Jiedu Jianpi Yiqi method in the treatment of liver cancer with good effect, can effectively alleviate the symptoms, improve the quality of life of patients.

关 键 词：清肝解毒 健脾益气 肝癌 

分 类 号：R273[医药卫生—中西医结合]