中国3省市21家医院早产发生的相关因素及结局研究  

Risk factors and perinatal outcomes for preterm birth in 21 health facilities in China

作　　者：王希[1] 康楚云[1] 高燕秋[1] 庞汝彦[1] 王燕[1] 

机构地区：[1]北京大学公共卫生学院妇女与儿童青少年卫生学系,100191

出　　处：《中国生育健康杂志》2014年第1期1-5,共5页Chinese Journal of Reproductive Health

基　　金：世界卫生组织母婴健康全球调查项目（210/108871-1）

摘　　要：目的 分析早产发生的影响因素与结局,为早产的防治工作提供依据. 方法 对3省市21家医院完成分娩的全部产妇13 322例进行调查,计算早产发生率,分析早产发生的相关因素,比较早产儿与足月儿的新生儿结局. 结果 早产发生率为6.0％,其中晚期早产（孕周34～36周）占77.3％;导致早产发生危险增加的因素有年龄＜20岁、年龄＞35岁、在校读书年数＞12年、多胎、发生妊娠合并症;早产导致死胎或死产,低、极低出生体重,Apgar得分≤7分,进入新生儿重症监护室,出院前或生后7d内死亡的危险增加. 结论 早产是威胁胎儿及新生儿健康的重要因素,应尽早识别具备早产危险因素的孕妇,以便及时开展针对性的治疗工作.Objective To explore the risk and avoidable factors for preterm birth and the perinatal outcomes of preterm birth. Methods All women given births in 21 hospitals across 3 provinces from November 2010 to January 2011 were included in the survey. The incidence d preterm birth was calculated. Univariate and multivariate logistic regression models were used to analyze the risk or avoidable factors for preterm birth. The perinatal outcomes were compared between the preterm and term births. Resulis Overall, 6. 0 % （ n = 803） of the study population delivered preterm births. Risk factors for preterm birth were maternal age 〈 20 years or 〉35 years, school years 〉 12, multiple pregnancy and maternal complications. The risk of stillbirth, low or very low birth weight, Apgar score ≤ 7, admission to neonatal intensive care unit and early neonatal death were increased among preterm births. Conclusion Preterm births are at increased risk of adverse perinatal outcomes. Defining risk factors for preterm birth is important because reliable identification of women at high risk would allow clinicians to implement targeted interventions.

关 键 词：早产 危险因素 围生儿结局 妊娠合并症 

分 类 号：R722.6[医药卫生—儿科]