气相色谱串联质谱法测定个人护理产品中的4种发热剂  

Determination of four self-heating compounds in personal care products by gas chromatography-tandem mass spectormetry

作　　者：赵田甜 李慧勇 谭建华 熊小婷 招启文 张可冬 夏泽敏 

机构地区：[1]广州市质量监督检测研究院,广东广州510110

出　　处：《现代化工》2014年第3期163-165,共3页Modern Chemical Industry

基　　金：国家质检总局科技计划项目(2012QK090);广州市质监局2014年科技计划项目

摘　　要：建立了化妆品中姜酮、香兰基丁醚、辣椒素、合成辣椒素4种发热剂的气相色谱串联质谱定性和定量分析方法.在优化的实验条件下,4种发热剂在0.5 ～ 100 mg/L范围内线性关系良好,空白样品在10.0、100.0、500.0 mg/kg 3个加标水平下,回收率为91％ ～ 109％,相对标准偏差为2.1％ ～6.2％.方法的定量下限（S/N=10）：香兰基丁醚、姜酮为5.0 mg/kg;辣椒素、合成辣椒素为10.0 mg/kg.该方法简单、快速、准确,可满足化妆品中4种发热剂的检测要求.A gas chromatography-tandem mass spectormetry （GC-MS） is developed for the qualitative and quantitative determination of four self-heating compounds in personal care products,including zingerone,vanilly butyl ether,N-vanillylonamide and capsaicin.Under the optimized conditions,the calibration curves of 4 self-heating compounds are linear in the range of 0.5-100 mg/L.The average recoveries of 4 compounds at three spiked levels of 10.0,100,500.0 mg/kg are between 91％-109％,with relative standard deviation of 2.1％-6.2％.The quantitation limits （S/N =10） of zingerone and vanilly butyl ether are 5.0 mg/kg,and those of capsaicin and N-vanillylonamide are 10.0 mg/kg.The method is simple,rapid and accurate,which can meet the requirements of the determination of 4 compounds in personal care products simultaneously.

关 键 词：发热剂 气相色谱串联质谱 个人护理产品 

分 类 号：O657.72[理学—分析化学] TQ658[理学—化学]