Steroidal saponins from the roots of Asparagus cochinchinensis  

作　　者：ZHU Guo-Lei HAO Qian LI Rong-Tao LI Hai-Zhou 

机构地区：[1]Faculty of Life Science and Technology,Kunming University of Science and Technology

出　　处：《Chinese Journal of Natural Medicines》2014年第3期213-217,共5页中国天然药物（英文版）

基　　金：supported by the National Natural Science foundation of China(No.20962013)

摘　　要：AIM： To study the chemical constituents of the roots of Asparagus cochinchinensis （Asparagaceae）. METHOD： The compounds were isolated with Diaion HP20, silica gel, and ODS chromatography, and their structures were de- termined on the basis of chemical methods, HR-ESI-MS, and 1 D- and 2D-NMR techniques. RESULTS： Seven compounds were isolated from the n-butanol fraction of the roots of A. cochinchinensis, and their structures were elucidated as （25S）-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22a, 26-triol-12-one-3-O-β-D-glucopyranoside （1）, （25S）-26- O-β-D-glucopyranosyl-22a-methoxy-5β-furostan-3p, 26-diol-12-one-3-O-β-D-glucopyranoside （2）, （25S）-26-O-β-D-glucopyra- nosyl-5β-furostan-3β, 22a, 26-triol （3）, （25S）-26-O-β-D-glucopyranosyl-5β-furstan-3β, 22a, 26-triol-3-O-β-D-glucopyranoside （4）, （25S）-26-O-β-D-glucopyranosyl-5β-furostan-3β, 22a, 26-triol-3-O-a-L-rhamnopyranosyl-（1, 4）-β-D-glucopyranoside （5）, （25S）- 5β-spirostan-3fl-ol-3-O-a-L-rhamnopyranoside （6）, and （25S）-5β-spirostan-3β-ol-3-O-β-D-glucopyranoside （7）. CONCLUSION： Compounds 1 and 2 were two new furostanol saponins.AIM:To study the chemical constituents of the roots of Asparagus cochinchinensis(Asparagaceae).METHOD:The compounds were isolated with Diaion HP20,silica gel,and ODS chromatography,and their structures were determined on the basis of chemical methods,HR-ESI-MS,and 1D- and 2D-NMR techniques.RESULTS:Seven compounds were isolated from the n-butanol fraction of the roots of A.cochinchinensis,and their structures were elucidated as(25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β,22α,26-triol-12-one-3-O-β-D-glucopyranoside(1),(25S)-26-O-β-D-glucopyranosyl-22α-methoxy-5β-furostan-3β,26-diol-12-one-3-O-β-D-glucopyranoside(2),(25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β,22α,26-triol(3),(25S)-26-O-β-D-glucopyranosyl-5β-furstan-3β,22α,26-triol-3-O-β-D-glucopyranoside(4),(25S)-26-O-β-D-glucopyranosyl-5β-furostan-3β,22α,26-triol-3-O-α-L-rhamnopyranosyl-(1,4)-β-D-glucopyranoside(5),(25S)-5β-spirostan-3β-ol-3-O-α-L-rhamnopyranoside(6),and(25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranoside(7).CONCLUSION:Compounds 1 and 2 were two new furostanol saponins.

关 键 词：Asparagus cochinchinensis ASPARAGACEAE Steroidal saponins 

分 类 号：R284.1[医药卫生—中药学]