小剂量多巴胺联合呋塞米在充血性心力衰竭中的应用价值研究  

Application value of low dose Dopamine combined with Furosemide in treating congestive heart failure

作　　者：夏晓芬 赵红娟 

机构地区：[1]浙江省临安市人民医院心血管内科,浙江临安311300

出　　处：《中国医药导报》2014年第9期110-112,共3页China Medical Herald

摘　　要：目的 研究小剂量多巴胺联合呋塞米在充血性心力衰竭中的应用价值.方法 将充血性心力衰竭患者纳入研究,随机分为给予小剂量多巴胺[0.5～1.0 μg/（kg·min）]联合呋塞米（20～40 mg/d）治疗的观察组和仅给予呋塞米治疗的对照组,观察治疗情况和心功能指标.结果 观察组患者的整体治疗效果优于对照组（总有效率95.6％比77.8％）,住院时间[（5.8±0.9）d比（8.7±1.3）d]、利尿剂抵抗例数（1例比4例）少于对照组,差异有统计学意义（P＜0.05）;观察组的E峰值、E/A比值、左心室射血分数、左心室舒张末期直径均低于对照组,差异有统计学意义（P＜0.05）.结论 小剂量多巴胺联合呋塞米治疗有助于改善治疗效果和心功能、控制利尿剂抵抗的发生,在充血性心理衰竭的治疗中具有积极价值.Objective To study the application value of low dose Dopamine combined with Furosemide in treating congestive heart failure.Methods Patients with congestive heart failure were enrolled and randomly divided into observation group whom were given low dose Dopamine [0.5-1.0 μg/（kg·min）] combined with Furosemide （20-40 mg/d） and control group whom were only given Furosemide.Then treatment condition and heart function index were observed.Results The overall effect of observation group was better than that of control group （total effective rate 95.6％ vs 77.8％）; hospitalization time [（5.8±0.9） d vs （8.7±1.3） d],diuretic resistance cases （1 case vs 4 cases） of observation group were lower than those of control group,the differences were statistically significant （P ＜ 0.05）; E peak,E/A ratio,LVEF,LVEDD of observation group were lower than those of control group,the differences were statistically significant （P ＜ 0.05）.Conclusion Low dose Dopamine combined with Furosemide has positive clinical value in treating congestive heart failure,it can improve the treatment effect and the heart function,control diuretic resistance.

关 键 词：充血性心力衰竭 多巴胺 呋塞米 利尿剂抵抗 心功能 

分 类 号：R541.61[医药卫生—心血管疾病]