T淋巴细胞亚群在口腔扁平苔癣发病机制中的作用  

作　　者：孙文玲[1] 和慧[1] 李振玲[1] 高爱超[1] 王晶晶[1] 郭婧芳[1] 

机构地区：[1]吉林大学口腔医院,吉林长春130021

出　　处：《医学美学美容（中旬刊）》2014年第1期226-227,共2页

摘　　要：口腔扁平苔癣（OLP）是最常见的口腔黏膜疾病之一,发病机制尚不明确,因其具有癌变潜能,WHO将其列为癌前状态。研究表明,T淋巴细胞亚群与口腔扁平苔癣的发病密切相关。本文就辅助性T细胞与OLP、调节性T细胞与OLP、细胞毒性T细胞与OLP等研究进展作一综述。Oral lichen planus （OLP） is a common oral mucosal disease in population,but its etiology still remains unkown. OLP has been classified as a precancerous condition for the malignant disease by Word Health Organization（WHO）. Previous studies have demonstrated there is a close relationship between T lymphocyte subjects and the pathogenesis of OLP. This paper will review the research progresses of Th1,Th2 cells and OLP,regulatory T cells and OLP,cytotoxic T lymphocyte and OLP,etc.

关 键 词：口腔扁平苔癣 T淋巴细胞亚群 细胞因子 Th1和Th2漂移学说 T细胞抵抗 反抑制 

分 类 号：R758.65[医药卫生—皮肤病学与性病学]