食管覆膜支架置入与扩张疗法治疗食管恶性狭窄疗效和安全性探讨  

The Efficacy and Safety of the Esophageal Covered Stent Placement and Expansion Therapy on 68 Cases with Esophageal Malignant Stricture

作　　者：周宇[1] 罗良德[1] 杨建[1] 申红[1] 

机构地区：[1]四川省三台县人民医院,四川三台621100

出　　处：《河北医学》2014年第3期488-491,共4页Hebei Medicine

摘　　要：目的:对比食管覆膜支架置入与扩张疗法治疗食管恶性狭窄的疗效和安全性。方法:68例食管恶性狭窄随机分为对照组和观察组,每组各为34例。对照组置入沙氏扩张探条;观察组置入镍钛记忆合金食道覆膜支架。比较两组置入成功率、疗效、梗阻改善状况、术后生活质量及并发症状情况。结果:观察组术后显效率和总有效分别达到82.36%和94.12%,显著高于对照组(P<0.05);观察组术后QOL生活质量评分为(42.30±6.52)分,显著高于术前和对照组术后评分(P<0.05);观察组术后总并发症率为8.82%,显著低于对照组并发症率14.71%(P<0.05),再狭窄率仅为5.88%,显著低于对照的14.71%(P<0.05)。结论:内镜下食管覆膜支架置入治疗食管恶性狭窄成功率高,能迅速缓解吞咽困难,术后患者生存质量高,并发症少,综合疗效显著优于沙氏扩张探条扩张。Objective：To compare the efficacy and safety between the Esophageal covered stent place-ment and expansion therapy on the cases with esophageal malignant stricture .Method：68 patients with ma-lignant esophageal stenosis were randomly divided into the control group and the observation group , each group had 34 cases.The control groups were implanted with Salmonella dilating bougie while the observation groups were implanted with nickel titanium memory alloy esophageal stent .The placement success rate , effi-cacy, the improvement of obstruction , the quality of life and complication after operation between two groups were compared .Results：The effective rate and total effective in the observation group reached 82.36%and 94.12%respectively, significantly higher than that of the control group （P＆lt;0.05）.The QOL quality of life score in the observation groups after treatment was （42.30 ＆#177;6.52） points, significantly higher than that of the preoperative and postoperative scores of the control groups （P＆lt;0.05）.The total the complication rate of＆amp;nbsp;the observation group was 8.82%, significantly lower than that of the control group （ P＆lt;0.05） and restenosis rate was only 5.88%, significantly lower than that of the control （P＆lt;0.05）.Conclusion： The Esophageal covered stent placement implanted on the esophageal malignant stricture had high success rate , with high quality of life and fewer complications , the curative effect was significantly better than the Sand＆#39;s expansion bougienage .

关 键 词：食管恶性狭窄 扩张疗法 食管覆膜支架置入 临床疗效 

分 类 号：R655.4[医药卫生—外科学]