活性炭对阿维菌素吸附效果的实验研究  

Experimental study on adsorption effect of activated carbon to abamectin

作　　者：陈宵[1] 郭翔[1] 李忠生[1] 于常艳[1] 肖经纬[1] 张宏顺[1] 李斌[1] 

机构地区：[1]中国疾病预防控制中心职业卫生与中毒控制所,北京100050

出　　处：《卫生研究》2014年第2期286-289,295,共5页Journal of Hygiene Research

基　　金：卫生行业科研专项项目(No.201202006-02);环保公益性行业科研专项(No.201109038);国家自然科学基金(No.81273110)

摘　　要：目的评价体外不同条件下活性炭对阿维菌素的吸附效果。方法用人工胃液、人工肠液配制浓度为10、5和2.5 g/L的阿维菌素溶液,分别调至pH1.9和pH6.8,设活性炭干预组和对照组,于孵育10 min、30 min、1 h、2 h和4 h后离心,紫外可见分光光度法测上清液中阿维菌素浓度,计算阿维菌素随时间的残留率和活性炭对阿维菌素的吸附率。结果 (1)在人工胃液与肠液环境中,不同炭药比(活性炭与阿维菌素质量比)时活性炭对阿维菌素均具有良好的吸附作用,并且存在时间依赖性;各个检测时间点活性炭对阿维菌素的吸附率(Q)均随炭药比的增加而递增。(2)活性炭-阿维菌素复合物的稳定性较强,在胃肠排空时间内基本不发生解离现象。结论活性炭吸附阿维菌素效果良好,且与炭药比呈正相关。Objective To investigate the adsorbability of activated charcoals for abamectin in vitro at various pH and concentrations. Methods Three concentrations of abamectin solutions（ 10, 5 and 2.5 g/L） with different pH value（ pill. 9 and pH6.8, respectively） were mixed with activated charcoal and control, respectively. The concentrations of abamectin were measured by UV-visible spectrophotometry after vibrated, incubated and centrifuged on different time points. Calculate the residue rate of abamectin and adsorption rate of activated carbon for avermectins. Results The abamectin was significantly decreased in activated charcoal group compared with control group and the absorption ability of activated charcoal was higher on low concentration of abamectin. Conclusion In vitro experiment showed that activated charcoal can significantly adsorb abamectin.

关 键 词：活性炭 阿维菌素 吸附 

分 类 号：R595.4[医药卫生—内科学] R136.3[医药卫生—临床医学]