标准化膀胱顺应性预测2～4岁小儿神经源性膀胱功能障碍上尿路扩张的研究  

Study of standard bladder compliance predicting upper urinary tract dilatation of neurogenic bladder dysfunction in children of 2-4 years old

作　　者：姚亚雄[1] 娄安峰[2] 冯帆[3] 

机构地区：[1]河南省焦作市第二人民医院,河南焦作454001 [2]郑州大学第一附属医院,郑州450052 [3]郑州大学第三附属医院,郑州450052

出　　处：《中国当代医药》2014年第8期68-70,共3页China Modern Medicine

摘　　要：目的 探讨标准化膀胱顺应性（Nwahl-1）是否能更好地预测神经源性膀胱功能障碍（NBD）患儿上尿路扩张（UUTD）.方法 随机选取54例不伴UUTD的无结石或其他尿路病变的2～4（3.16±0.11）岁NBD患儿,进行侵入性尿流动力学检查后随访2年,根据2年后泌尿系造影和B超检查结果,将有UUTD的21例患儿作为UUTD组,其余33例为无UUTD组;应用单因素方差分析和受试者工作特征曲线分析Nwahl-1预测UUTD的可能性.结果 Nwahl-1是2～4岁NBD患儿2年后并发UUTD的相关因素,以Nwahl-1＜19.39为指标能较为准确地预测NBD患儿2年后并发UUTD,灵敏度为87.9％,特异度为81.0％.结论 NWahl-1能较准确地预测2～4岁NBD患儿2年后发生UUTD.Objective To evaluate standard bladder compliance （Nw）whether could better predict upper urinary tract dilatation （UUTD） of neurogenic bladder dysfunction （NBD） in children of 2-4 years old. Methods 54 children of 2-4 （3.16＋0.11） years old with NBD but had no UUTD and without the stones and other urinary tract lesions were conduct- ed invasive urodynamic examination,after that,they were followed-up for 2 years,they were divided into the UUTD group （n=21） cases and no UUTD group （n=33） according to urography and the examination results of B ultrasound.The prob- ability of Nw-1 predicting UUTD were analyzed by one-factor analysis of variance and receiver operating characteristic （ROC） curve. Results Nw-1 was the related factors of complicating UUTD in children with NBD of 2-4 years old after 2 years,Nwm- 〈19.39 was selected as as the index and the sensitivity was 87.9%, specificity was 81.0%. Conclusion Nw-I can accurately predict children of 2-4 years old with NBD having UUTD.

关 键 词：膀胱顺应性 神经源性膀胱功能障碍 上尿路扩张 

分 类 号：R691.9[医药卫生—泌尿科学]