干细胞技术在内分泌代谢病中的研究进展  

Progress of stem cell technology in the study of endocrine and metabolic diseases

作　　者：魏蕊[1] 洪天配[1] 

机构地区：[1]北京大学第三医院内分泌科,100191

出　　处：《中华内分泌代谢杂志》2014年第3期250-253,共4页Chinese Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金资助项目（81270858）;高等教育博士学科点新教师基金资助项目（20120001120063,20120001120076）

摘　　要：干细胞具备自我更新和多向分化的潜能，是糖尿病细胞替代治疗的理想细胞来源。此外，干细胞在多种内分泌器官的胚胎发育研究、内分泌代谢疾病的发病机制、药物筛选等方面也具有潜在的应用前景。Stem cells with the capacity of self-renewal and multilineage differentiation are promising sources for generation of pancreatic cells for cell replacement therapy in diabetes mellitus. Stem cells also show their potential in the studies regarding the embryonic development of several endocrine organs including pancreatic islets, thyroid, parathyroid, and adrenal glands. Moreover, they would be much useful for investigation of pathogenesis and drug screening in endocrine and metabolic diseases.

关 键 词：干细胞 胰岛 甲状腺 甲状旁腺 肾上腺 

分 类 号：R589[医药卫生—内分泌]