中国畲族人群血脂异常患病率及危险因素分析  

Dyslipidemia and associated risk factors in She ethnic minority group of China

作　　者：陈年慧[1] 刘菁[1] 陈刚[1] 

机构地区：[1]福建医科大学省立临床医学院内分泌科,福州350003

出　　处：《中华糖尿病杂志》2014年第2期101-105,共5页CHINESE JOURNAL OF DIABETES MELLITUS

摘　　要：目的 探讨中国福建省畲族人群的血脂异常患病率和流行病学特征.方法 2009年4月到9月在福建宁德地区福鼎市桐城街道、前歧镇和沙埕镇采用随机整群分层抽样方法随机抽取4 838名畲族人进入研究.测量身高、体重和血压,并测定血总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）和甘油三酯（TG）.应用不同标准对受试者进行分组并使用x2检验和多因素logistic回归对血脂情况进行统计分析.结果 共有1 285名参与者血脂异常（患病率26.6％）,其中高TC血症、高LDL-C血症、低HDL-C血症和高TG血症的患病率分别是10.1％（488/4 838）、12.6％ （609/4 838）、5.2％ （252/4 838）和11.4％ （551/4 838）；男女性血脂异常患病率为30.0％ （617/2 057）和24.0％ （667/2 781）,差异具有统计学意义（x2=21.91,P＜0.05）.血脂异常的患病率随年龄增长的差异有统计学意义（x2=30.89,P＜0.05）,并且与性别、体质指数、空腹血糖、血压密切相关（OR=0.656、1.146、1.059、1.457,均P＜0.05）.结论 畲族人群的血脂异常患病率较高,有必要加强患者的管理,进行综合干预.Objective To investigate the prevalence of dyslipidemia and associated risk factors in adult She nationality population in Fujian Province.Methods Total of 4 838 adults selected from urban and rural areas of Ningde （Tongcheng Subdistrict in Fuding City,Qianqi Town,Shacheng Town）,Fujian Province from April 2009 to September 2009 by multi-stage stratified sampling,completed the survey and physical measurements.The height,weight,blood pressure and serum total cholesterol,high-density lipoprotein cholesterol （HDL-C）,low-density lipoprotein cholesterol （LDL-C）,triglycerides were detected and analyzed by chi-square test and multivariate logistic regression analysis among the different groups.Results The overall prevalence of dyslipidemia was 26.6％,the prevalence of dyslipidemia was higher in males than that in females （30.0％ （617/2 057） vs 24.0％ （667/2 781）,x2 =21.91,P ＜0.05） The prevalence of high total cholesterol （TC）,high LDC-C,low HDL-C and hypertriglyceridemia were 10.1％ （488/4 838）,12.6％ （609/4 838）,5.2％ （252/4 838） and 11.4％ （551/4 838）,respectively.The prevalence of dyslipidemia increased with age （x2 =30.89,P ＜ 0.05） and was associated with sex,body mass index,fasting glucose and blood pressure （OR =0.656,1.146,1.059,1.457,respectively,all P ＜ 0.05）.Conclusion Dyslipidemia is a major public health problem in She population.Steps must be taken to prevent and treat dyslipidemia in She population.

关 键 词：畲族人群 血脂异常 患病率 危险因素 

分 类 号：R589.2[医药卫生—内分泌]