2型糖尿病住院患者血脂异常的特点分析  

Patterns of dyslipidemia in patients with type 2 diabetes

作　　者：曲捷[1] 贾勤惠[1] 王国锋 

机构地区：[1]解放军兰州军区乌鲁木齐总医院干部病房,新疆乌鲁木齐830000 [2]解放军空军乌鲁木齐基地后勤部门诊部,新疆乌鲁木齐830000

出　　处：《临床军医杂志》2014年第2期140-142,共3页Clinical Journal of Medical Officers

摘　　要：目的研究2型糖尿病(T2DM)住院患者的血脂异常特点,并分析其与糖尿病病程及控制的关系。方法回顾性横断面研究。纳入216例(男96例,女120例)于2010年4月—2013年4月在我院干部病房住院的所有T2DM患者。收集人口学基本资料以及糖尿病病程、高血压病史、糖化血红蛋白、血脂以及血肌酐等临床资料。结果入组人员中最常见的血脂异常类型为高密度脂蛋白异常(51.9%),有81%的入组人员至少有1种类型的血脂异常。经校对后,糖尿病病程与三酰甘油异常、低密度脂蛋白异常、高密度脂蛋白异常显著相关,而控制达标与四种血脂异常类型均显著相关。结论T2DM人群中血脂异常患病率远高于一般人群,且糖尿病病史越长、控制不达标均增加血脂异常的患病风险。Objective To explore the patterns of dyslipidemia in patients with type 2 diabetes mellitus （T2DM）, and to determine the association among dyslipidemia, T2DM duration and glycemie control. Methods The retrospective cross-sectional study was conducted among 216 consecutive T2DM inpatients during April 2010 to April 2013. Data of demography, diabetic profile, lipid and serum creatinine were collected. Results Most common form （51. 9% ） of dyslipidemia was low high-density lipoprotein （HDL）. Around 81% of the studied subjects had at least one lipid abnormality. After adjusted, T2DM duration was significantly associated with increased risk of high triglyeeride, low-density lipoprotein （LDL） and low HDL. Glycemie control was significantly associated with each form of dyslipidemia. Conclusion The prevalence of dyslipidemia in T2DM is higher than that in general population. Prolonged duration and poor glycemic control predicts dyslipidemia in T2DM.

关 键 词：糖尿病 血脂 胆固醇 脂蛋白 

分 类 号：R587.1[医药卫生—内分泌]