血清抵抗素与吸烟者动脉弹性的相关性研究  

Correlation study of serum resistin and artery elasticity function in smokers.

作　　者：王立坤[1] 姚海英 武雪亮[3] 王义成[1] 温德惠[1] 

机构地区：[1]河北北方学院附属第一医院超声医学科,河北张家口075000 [2]万全县医院超声科,河北张家口076250 [3]河北北方学院附属第一医院血管腺体外科,河北张家口075000

出　　处：《海南医学》2014年第6期802-804,共3页Hainan Medical Journal

基　　金：河北省计生委2012年指导性计划(编号:2012-A28);河北省卫生厅2012年科学技术研究与发展指导计划资助项目(编号:20120417)

摘　　要：目的测定吸烟者血清抵抗素水平,并行颈动脉ET技术(血管回声跟踪技术)检测,探讨血清抵抗素水平与动脉弹性的关系。方法选择非吸烟者38例,吸烟者45例,检测血压、身高、体重、体重指数(BMI)、生化指标、血清抵抗素水平,并应用ET技术检测颈动脉压力应变弹性系数(Ep)、僵硬度(β)、顺应性(AC)、增大指数(AI)及脉搏波传导速度(PWVβ)。结果 (1)吸烟组Ep、β、AI及PWVβ均高于非吸烟组,差异有统计学意义(P<0.05);AC低于非吸烟组,差异有统计学意义(P<0.05)。(2)血清抵抗素水平与β、PWVβ呈正相关关系(r=0.346,P=0.003;r=0.305,P=0.009)。结论吸烟者血清抵抗素水平与β、PWVβ有相关性,三者均是早期发现动脉弹性病变的敏感指标。Objective To study the relationship of the level of serum resistin and artery elasticity function by measuring the level of serum resistin in smokers and detecting E-tracking technique of carotid artery. Methods Forty-five smokers （smokers group） and thirty-eight non-smokers （non-smokers group） were selected. Blood Pressure, height, weight, body mass index （BMI）, biochemical index and level of serum resistin were detected, and pressure-strain elastic modulus （Ep）, stiffness parameters （fl）, arterial compliance （AC）, augment index （AI）, and pulse wave conducting velocity （PWVfl） of Carotid Artery were measured by E-Tracking Technology. Results （1） Ep, fl, AI and PWVfl in smokers group were higher than those in non-smokers group, and there was statistically significant difference （P〈0.05）. AC in smokers group were lower than that in non-smokers group, and there was statistically significant difference （P〈0.05）. （2） The level of serum resistin was positively related with fl and PWVfl （r=0.346, P=0.003; r=0.305, P=0.009）. Conclusion The level of serum resistin has correlation with/3 and PWV/3. Furthermore, serum resistin, 13 and PWVI3 are sensitive indexes of early-detecting artery elasticity lesions.

关 键 词：抵抗素 吸烟 颈动脉 血管回声跟踪技术 

分 类 号：R392.7[医药卫生—免疫学]