血府逐瘀汤联合强痛定治疗瘀血内阻型癌症疼痛随机平行对照研究  

Xuefu Zhuyu Decoction Combined with Fortanodyn Treating Blood Stasis Type of Cancer Pain

作　　者：樊杜英[1] 罗溢昌[1] 

机构地区：[1]广州市中医医院肿瘤一区,广州510000

出　　处：《实用中医内科杂志》2014年第1期109-111,共3页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[目的]观察血府逐瘀汤联合强痛定治疗瘀血内阻型癌症疼痛疗效。[方法]使用随机平行对照方法,将100例住院患者按住院顺序随机分为两组。对照组50例三阶梯止痛疗法常规应用止痛药物,强痛定,0.6g/次,3次/d,口服。治疗组50例血府逐瘀汤(桃仁、延胡索、当归各15g,川牛膝、川穹、红花、生地黄、乳香各10g,枳壳、桔梗、赤芍各6g,炙甘草、柴胡、三七粉冲服各3g,白花蛇舌草30g),1剂/d,前10d水煎200mL,早晚口服;后20d,上述药物粉碎制成水丸,10g/次,3次/d,口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组痊愈4例,显效32例,有效12例,无效2例,总有效率96.00%。对照组痊愈1例,显效24例,有效16例,无效9例,总有效率82.00%。治疗组疗效优于对照组(P<0.01)。[结论]血府逐瘀汤联合强痛定在治疗瘀血内阻型癌症疼痛效果显著,值得推广。[ Objective ] To observe the Xuefu Zhuyu Decoction Combined with fortanodyn efficacy in the treatment of blood stasis type of cancer pain. [ Methods ] Using randomized controlled methods, 100 cases of hospitalized patients were randomly divided into two groups. A control group of 50 cases three step analgesic ladder routine application of analgesic drugs, AP-237, 0.6g/, 3 /d, oral. The treatment group of 50 cases of Xuefu Zhuyu Decoction （Taoren, Yanhusuo, Dangui each 15g, Chuanniuxi, Chuanxiong, Honghua,Shengdihua, Ruxiang each 10g, Jike, Jiegeng, Chishao each 6g, Zhigancao, Chaihu, Sanqifen blunt each 3g, Baihuasheshecao 30g ）, 1 doses of/d, the former 10d of water fried 200mL, sooner or later oral; after 20d, the drug is crushed into water pill, 10g/, 3/d, oral western medicine treatment with the control group. Continuous treatment with 30d for 1 courses. Observation of clinical symptoms, adverse reaction. Continuous 3 courses of treatment, the curative effect. [ Results ] The treatment group cured 4 cases, effective in 32 cases, effective 12 cases, invalid 2 eases, the total efficiency of 96%. The control group cured 1 cases, effective in 24 cases, effective 16 cases, invalid 9 cases, the total efficiency of 82%. The treatment group was better than control group （ P~ 0.01 ） . [ Conclusion ] Xuefu Zhuyu Decoction Combined with fortanodyn significantly in pain treatment of blood stasis type of cancer, worthy of promotion.

关 键 词：瘀血内阻型癌症疼痛 血府逐瘀汤 强痛定 随机平行对照研究 

分 类 号：R273[医药卫生—中西医结合] R289.5[医药卫生—中医肿瘤科]