全身磁共振扩散加权成像在淋巴结病变的应用研究现状与进展  

Status and developments of whole body MR diffusion weighted imaging in lymph node lesions

作　　者：陈淑香[1] 尹化斌[1] 

机构地区：[1]复旦大学附属上海市第五人民医院放射科,200240

出　　处：《国际医学放射学杂志》2014年第2期110-114,共5页International Journal of Medical Radiology

摘　　要：淋巴结病变特别是淋巴瘤和转移性淋巴结多为全身性的,目前临床上常用的评估方法多为局部检查,且主要依赖于形态学改变,故有较大的局限性。全身MR扩散加权成像(WB MR DWI)是在自由呼吸下的一站到位的全身检查,对发现全身淋巴结病变有很大的潜力,而且无辐射,对特定人群如儿童病人更有优势。其对治疗前后变化不大或较小的淋巴结病变在放化疗后发生的微观变化较为敏感,结合ADC值能在病变发生形态学变化前定量评估其微观病理过程,从而有助于淋巴结病变的诊断、鉴别诊断、治疗方案制定与调整、疗效评估以及指导穿刺活检等,提示WB MRI DWI在全身性病变,特别是对于淋巴瘤和转移性淋巴结有很好的研究价值和临床应用前景。Lymphoma and lymph node metastasis are the main cause of systemic lymphadenopathy.Conventional imaging methods are usually used to evaluate the local morphological changes,such as the lymph node changes in shape and size.While whole body magnetic resonance diffusion weighted imaging has no radiation,can be safely used for evaluation of lymph node without breath-holding in specific populations,such as children.It is sensitive to the pathological changes of lymph node pre-and post-radiochemical treatment.Combining with apparent diffusion coefficient measurement,it can quantitatively evaluate the pathological changes.It is useful in diagnosis,differential diagnosis,treatment response assessment,and guiding biopsy.We reviewed the applications of this technique in systemic diseases,especially in lymphoma and metastatic lymph node lesions.

关 键 词：淋巴结 淋巴结病变 淋巴瘤 转移 全身磁共振扩散加权成像 

分 类 号：R551.204[医药卫生—血液循环系统疾病]