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出 处:《广州中医药大学学报》2014年第2期220-223,共4页Journal of Guangzhou University of Traditional Chinese Medicine
基 金:海南省自然科学基金项目(编号:310194)
摘 要:【目的】观察中药泡脚配合穴位贴敷治疗稳定期慢性阻塞性肺疾病(COPD)的临床疗效。【方法】将148例患者随机分为治疗组75例和对照组73例,治疗组给予中药泡脚配合穴位贴敷治疗,对照组给予中药穴位贴敷治疗,观察2组治疗前后临床症状体征、3年内COPD急性发作次数、生活质量、肺功能指标的变化情况,并评价其临床疗效。【结果】(1)治疗组总有效率为92.0%,对照组为73.9%,治疗组疗效优于对照组(P<0.05)。(2)治疗后,除咳嗽外,2组的临床症状体征均显著改善(P<0.01),且治疗组的改善作用优于对照组(P<0.05或P<0.01)。(3)2组3年内COPD急性发作次数比较,差异有统计学意义(P<0.05),提示治疗组可减少COPD急性发作次数。(4)治疗后,除对照组的日常生活能力外,2组的生活质量评分均显著改善(P<0.01),且治疗组的改善作用优于对照组(P<0.01)。(5)治疗后,2组患者的肺功能指标FEV1、FEV1/FVC均显著提高(P<0.05),但治疗后2组比较差异无统计学意义(P>0.05)。【结论】中药泡脚配合穴位贴敷治疗稳定期慢性阻塞性肺疾病疗效显著。Objective To observe the curative effect of Chinese medicine foot bath combined with acupoint application for stable chronic obstructive pulmonary disease (COPD) . Methods One hundred and forty-eight stable COPD patients were randomly divided into treatment group (N=75) and control group (N=73) . The treatment group was given Chinese medicine foot bath combined with acupoint application, and the control group was given acupoint application. After treatment, the curative effect was evaluated in the two groups. Meanwhile, the changes of clinical symptoms and signs, frequency of COPD acute attack within 3 years, quality of life (QOL), and pulmonary function of the two groups were also observed. Results (1) The total effective rate of the treatment group was 92.0%, and that of the control group was 73.9%, the difference being significant (P〈0.05). (2) After treatment, all symptoms and signs except cough were relieved in both groups (P〈O.O1), and the relief was more obvious in the treatment group (P〈0.05 or P〈0.01). (3) The frequency of COPD acute attack within 3 years was reduced in the treatment group compared with that in the control group (P〈0.05). (4) After treatment, the scores of QOL except for the daily activities were much improved in both groups (P〈O.O1), and the improvement in the treatment group was superior to that in the control group (P〈0.01). (5) After treatment, lung function indexes of forced expiratory volume in one second (FEV1) and the percentage of FEV1 (FEV1/FVC) were markedly increased in both groups (P〈O.05 compared with those before treatment), but the differences between the two groups were insignificant (P〉0.05). Conclusion Chinese medicine foot bath combined with acupoint application exerts certain therapeutic effect for stable COPD.
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